Trabajo Original
Effect of grape juice consumption on antioxidant activity and interleukin-6 concentration in lactating rats
Sabrina Baptista Alves Faria, Vanessa Rosse, Juliana Furtado Dias, Nara Moreira Xavier, Vilma Blondet Azeredo
Número de descargas:
2472
Número de visitas:
8711
Citas:
2
Compártelo:
Objective: This study evaluated the effect of grape juice consumption on the antioxidant capacity and the interleukin-6 blood level of lactating rats. Material and method: Eighteen Wistar rats, lactating females adult, were divided into two groups: control group (CG) and grape juice group (GJG). The antioxidant activity was determined by the method of 2,2-diphenyl-1-picrylhydrazyl (DPPH)-kidnapping of free radicals (DPPH) and oxygen radical absorbance capacity (ORAC), and the interleukin-6 was determined by Enzyme-Linked Immunosorbent Assay (ELISA) method. The data were presented as mean and standard deviation. Results: The antioxidant capacity was higher (p < 0.05) in the GJG (25.00 ± 3.08 µmol eq. Trolox/g) than in the CG (10.00 ± 3.11 µmol eq. Trolox/g), by the ORAC method. The interleukin-6 (pg/ml) level was lower in the grape juice group than in CG. Conclusion: The consumption of grape juice during lactation improves the antioxidant capacity in lactating rats and seems capable to decrease the inflammatory activity.
Palabras Clave: Lactation. Grape juice. Antioxidant activity. Interleukin-6. Wistar rats.
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