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Nutrición Hospitalaria 01792 / http://dx.doi.org/10.20960/nh.1792
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Dysbiosis and metabolic endotoxemia induced by high-fat diet

Thalita Lin Netto Candido, Josefina Bressan, Rita De Cássia Gonçalves Alfenas

VOLUMEN 35, NÚM. 6, noviembre-diciembre (2018), PAG. 1432-1432

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Introduction: diet plays a decisive role in the prevention and treatment of diseases such as obesity, diabetes, allergies and inflammatory diseases. In addition to this, there are numerous investigations about the role of the microbiota in the genesis of metabolic diseases, especially obesity and its comorbidities.Objective: the aim of this review is to discuss the influence of high-fat diets on dysbiosis and metabolic endotoxemia.Results and conclusion: the intestinal microbial ecosystem has been shown to be essential in the performance of functions in the host organism, however, several factors can lead to an imbalance in the homeostasis of the microbiota, known as dysbiosis. High-fat diets are associated with a reduction in intestinal bacterial diversity, changes in membrane integrity, inducing increased permeability and increased lipopolysaccharide (LPS) translocation, changes in the immune system, and generation of low-intensity systemic inflammation. The installed endotoxemia can be considered as a causal factor of subclinical inflammation related to several chronic diseases, and as a result of this, it is essential to know the real impact of hyperlipidic diets on the intestinal microbiota. Thus, it becomes essential to identify dietary strategies that can minimize the inflammatory effects generated from changes in the intestinal microbiota.

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Alves de Bessa, Camila, Secco Rossetti, Bianca, Gabrielly Ferreira Chaves, Giordanna, Rodrigues Costa Melo, Raiana (2023) Análise da relação entre obesidade e microbiota intestinal:. Brazilian Medical Students
Chen, Yuhua, Zhang, Lei, Zhang, Yongbo, Bai, Tao, Song, Jun, Qian, Wei, Hou, Xiaohua (2020) EphrinA1/EphA2 Promotes Epithelial Hyperpermeability Involving in Lipopolysaccharide-induced Intestinal Barrier Dysfunction. Journal of Neurogastroenterology and Motility
Mohammad, Shireen, Thiemermann, Christoph (2021) Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions. Frontiers in Immunology
Fan, Shuyi, Chen, Suyun, Lin, Lin (2023) Research progress of gut microbiota and obesity caused by high-fat diet. Frontiers in Cellular and Infection Microbiology
Wang, Peng, Zhang, Xiaoqi, Zheng, Xian, Gao, Jingru, Shang, Mengfei, Xu, Jinghan, Liang, Hui (2022) Folic Acid Protects against Hyperuricemia in C57BL/6J Mice via Ameliorating Gut–Kidney Axis Dysfunction. Journal of Agricultural and Food Chemistry
Koh, Gar Yee, Wang, Yu (2022) Implications of type 1 and type 2 taste receptors on obesity-induced inflammation. Journal of Food Bioactives
Guo, Yingjie, Yu, Yanan, Li, Hailong, Ding, Xueli, Li, Xiaoyu, Jing, Xue, Chen, Jianwei, Liu, Guilin, Lin, Yuan, Jiang, Chen, Liu, Zhen, He, Yuwei, Li, Changgui, Tian, Zibin (2021) Inulin supplementation ameliorates hyperuricemia and modulates gut microbiota in Uox-knockout mice. European Journal of Nutrition
Stepanov, Yu.M., Zavhorodnia, N.Yu., Zhyhyr, N.O. (2022) The role of the intestinal permeability in the progression of nonalcoholic fatty liver disease in obese children. GASTROENTEROLOGY
Ma, Qianqian, Ma, Jiaojiao, Cui, Jinxiu, Zhang, Chenxu, Li, Yuanzhe, Liu, Juan, Xie, Kangning, Luo, Erping, Tang, Chi, Zhai, Mingming (2023) Oxygen enrichment protects against intestinal damage and gut microbiota disturbance in rats exposed to acute high-altitude hypoxia. Frontiers in Microbiology
Usman, Iqra, Anwar, Aamir, Shukla, Shivang, Pathak, Priya (2024) Mechanistic Review on the Role of Gut Microbiota in the Pathology of Cardiovascular Diseases. Cardiovascular & Hematological Disorders-Drug Targets
Fadieienko, G., Gridnev, А. , Kushnir, I., Solomentseva, T. , Chernova, V. , Galchіnskaya, V. (2023) The Role of Intestinal Microbiota, Endotoxemia and Systemic Inflammation in the Pathogenesis of Nonalcoholic Fatty Liver Disease. Lviv clinical bulletin
Yu, Shenglan, Jiang, Jiarui, Li, Qinqin, Liu, Xuan, Wang, Zhengtao, Yang, Li, Ding, Lili (2022) Schisantherin A alleviates non-alcoholic fatty liver disease by restoring intestinal barrier function. Frontiers in Cellular and Infection Microbiology
Shi, Ke, Zhou, Tao, Yuan, Yu‐fei, Li, Dan‐dan, Gong, Bin‐bin, Gao, Shan, Chen, Qi‐jia, Li, Yan‐dong, Han, Xue (2023) Synergistic mediating effect of edible fungal polysaccharides (Auricularia and Tremellan) and Crataegus flavonoids in hyperlipidemic rats. Food Science & Nutrition
Alemasi, Akehu, Gu, Lijiang, Zhou, Yilun (2024) Gut microbiota in the association between obesity and kidney function decline: a metagenomics-based study in a rat model. Renal Failure
Bilal, Muhammad, Ashraf, Shoaib, Zhao, Xin (2022) Dietary Component-Induced Inflammation and Its Amelioration by Prebiotics, Probiotics, and Synbiotics. Frontiers in Nutrition
Chopra, Sunil, Dahiya, Vandana, Saini, Anu, Pandey, Ramendra Pati (2025) A narrative review on the role of gut microbiome, dietary strategies, and supplements in managing metabolic syndrome. Exploration of Drug Science
Mundula, Tiziana, Russo, Edda, Curini, Lavinia, Giudici, Francesco, Piccioni, Andrea, Franceschi, Francesco, Amedei, Amedeo (2022) Chronic Systemic Low-Grade Inflammation and Modern Lifestyle: The Dark Role of Gut Microbiota on Related Diseases with a Focus on COVID-19 Pandemic. Current Medicinal Chemistry
Ghosh, Siddhartha S., Ghosh, Shobha (2020) HMGB1 (High-Mobility Group Box-1). Arteriosclerosis, Thrombosis, and Vascular Biology
Qiao, Bo, Li, Xiaoya, Zheng, Tao, Tan, Zhoujin (2022) Different Effects of Lard and Vegetable Blend Oil on Intestinal Microorganisms, Enzyme Activity and Blood Routine in Mice. Journal of Oleo Science
Sirin, Fevziye Burcu, Korkmaz, Hakan, Torus, Bora, Bozkurt, Mustafa, Kumbul Doguc, Duygu (2021) The role of zonulin in the pathogenesis of diabetic retinopathy. Turkish Journal of Biochemistry
Longoria, Candace R., Guers, John J., Campbell, Sara C. (2022) The Interplay between Cardiovascular Disease, Exercise, and the Gut Microbiome. Reviews in Cardiovascular Medicine
Okyere, Samuel Kumi, Wen, Juan, Cui, Yujing, Xie, Lei, Gao, Pei, Zhang, Ming, Wang, Jianchen, Wang, Shu, Ran, Yinan, Ren, Zhihua, Hu, Yanchun (2022) Bacillus toyonensis SAU-19 and SAU-20 Isolated From Ageratina adenophora Alleviates the Intestinal Structure and Integrity Damage Associated With Gut Dysbiosis in Mice Fed High Fat Diet. Frontiers in Microbiology
Villette, Remy, KC, Pukar, Beliard, Sophie, Salas Tapia, Maria Fernanda, Rainteau, Dominique, Guerin, Maryse, Lesnik, Philippe (2020) Unraveling Host-Gut Microbiota Dialogue and Its Impact on Cholesterol Levels. Frontiers in Pharmacology
Xu, Daxing, Lv, Qiulan, Wang, Xiaofeng, Cui, Xuena, Zhao, Peng, Yang, Xiaomin, Liu, Xiu, Yang, Wan, Yang, Guanpin, Wang, Guangtao, Wang, Pengjun, Wang, Zenglan, Li, Zhiyuan, Xing, Shichao (2019) Hyperuricemia is associated with impaired intestinal permeability in mice. American Journal of Physiology-Gastrointestinal and Liver Physiology
Skoracka, Kinga, Hryhorowicz, Szymon, Rychter, Anna Maria, Ratajczak, Alicja Ewa, Szymczak-Tomczak, Aleksandra, Zawada, Agnieszka, Słomski, Ryszard, Dobrowolska, Agnieszka, Krela-Kaźmierczak, Iwona (2023) Why are western diet and western lifestyle pro-inflammatory risk factors of celiac disease?. Frontiers in Nutrition

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