Acceso gestor editorial

Effects of red wine, grape juice and resveratrol consumption on bone parameters of wistar rats submitted to high-fat diet and physical training

Letícia Monteiro Da Fonseca Cardoso , Nina Da Matta Alvarez Pimenta , Raiza Da Silva Ferreira Fiochi , Bruna Ferreira Mota Mota , Juliana Arruda De Souza Monnerat , Cristiane Correia Teixeira , Renata Beatriz Da Rocha Ramalho , Isabelle Waleska Maldronato , Manuela Dolisnky , Gilson Teles Boaventura , Vilma Blondet , Sergio Girão Barroso , Carlos Alberto Soares Da Costa , Gabrielle De Souza Rocha

Resumen

Introduction: intake of diets with high saturated fat may produce deleterious effects on bone mineralization. Lifestyle changes help reduce the bone loss observed in osteoporosis. Resveratrol, present in grape juice and red wine, has osteogenic and osteoinductive effects, being potentially beneficial for bone health.Objective: to evaluate the effects of red grape juice, red wine and resveratrol consumption on bone parameters in Wistar rats submitted to a high-fat diet and physical training. Method: female Wistar rats, with 90 days of age, were divided into five groups and followed up for 60 days: a) control group; b) high-fat group; c) grape juice group; d) red wine group; and e) resveratrol group. The different groups of animals performed a physical training protocol. Animal’s weight and consumption were monitored weekly. After 60 days, femoral dimensions, bone mineral density (BMD) and bone mineral content (BMC) were evaluated. Results: there was no difference in body mass; however, all groups consuming the high-fat diet had higher consumption (p < 0.05). RWG presented a greater distance between the epiphyses, femoral mass and BMC (p < 0.05). RWG and RG presented greater mean diaphysis point width and BMD (p < 0.05). Conclusion: the results suggest that the bioactive compounds present in red wine and resveratrol solution together with regular exercise were able to promote beneficial effects on bone health, even when associated with a high saturated fat diet.

Palabras Clave

High-fat diet, resveratrol, grape juice, red wine, physical activity, bone health.


Texto Completo: PDF (ENGLISH)


Nº de Visitas: 28
Nº de Descargas: 0

Una cookie o galleta informática es un pequeño archivo de información que se guarda en su navegador cada vez que visita nuestra página web.

La utilidad de las cookies es guardar el historial de su actividad en nuestra página web, de manera que, cuando la visite nuevamente, ésta pueda identificarle y configurar el contenido de la misma en base a sus hábitos de navegación, identidad y preferencias.

Las cookies pueden ser aceptadas, rechazadas, bloqueadas y borradas, según desee. Ello podrá hacerlo mediante las opciones disponibles en la presente ventana o a través de la configuración de su navegador, según el caso.

En caso de que rechace las cookies no podremos asegurarle el correcto funcionamiento de las distintas funcionalidades de nuestra página web.

Más información en el apartado “POLÍTICA DE COOKIES” de nuestra página web.