Xinxin Chen
Número de descargas:
62
Número de visitas:
811
Compártelo:
Objective: transarterial chemoembolization (TACE) is one of the common treatments for hepatocellular carcinoma (HCC). Predicting prognosis for HCC patients who received TACE is challenging because of huge differences in outcome. At present, the Nutritional Risk Screening 2002 (NRS-2002) is widely used to screen nutritional risk in hospitalized patients, which has been confirmed to be related to prognosis. Here, the objective of this research is to construct a prognostic nomogram using the NRS-2002 score for HCC patients receiving TACE. Methods: we enrolled 359 HCC patients who received TACE at the Xingtai People's Hospital between January 2015 and December 2020. According to the preoperative NRS-2002 score, patients were divided into an NRS ≥ 3 group (n = 190; 52.9 %) and an NRS < 3 group (n = 167, 47.1 %). Meanwhile, variables associated with survival were analyzed by univariate and multivariate Cox regression. Beyond that, a nomogram incorporating independent variables was established. The concordance index (C-index) and calibration curves were used to assess the prediction performance of the nomogram. Results: the median survival of the NRS ≥ 3 group was significantly lower than that of the NRS < 3 group. As shown by multivariate analysis, in the Barcelona Clinic Liver Cancer stage an NRS-2002 score ≥ 3, γ-glutamyl transpeptidase, and alpha-fetoprotein were significantly associated with survival in HCC patients after TACE. In addition, the C-index was 0.708 (95 % confidence interval: 0.672-0.743), and the calibration curves showed a good consistency between the observed and predicted survivals at 1, 2, and 3 years, respectively. Conclusions: NRS-2002 ≥ 3 could identify high-risk patients with HCC who received TACE. The NRS-2002-based nomogram model had good prognostic prediction accuracy. Keywords:
Palabras Clave: Hepatocellular carcinoma. Transcatheter arterial chemoembolization. Nutritional risk. Nutritional risk screening 2002.
Dino Moretti , Melisa D. Ré , Nicolás S. Rocchetti , Daniel Horacio Bagilet , Claudio Jesus Settecase , Martin Buncuga , Marta Quaglino
Jorge Luis Gutiérrez De Santiago , Sandra Aguilar Valdez , Myrella Leticia Casas Robles , Idalia Garza Veloz , Vicente Ortega Cisneros , Margarita de la Luz Martínez Fierro
Daniella Miranda da Silva , Ana Cristhina Henz , Sabrina Alves Fernandes , Cláudio Augusto Marroni
Yuanfeng Gong , Fengying Dong , Yan Geng , Hongkai Zhuang , Zuyi Ma , Zixuan Zhou , Bowen Huang , Zhonghai Sun , Baohua Hou
Sheila Alejandra Campos León , Agustín Ramiro Urzua González , Manuel José Rivera Chávez , María de Lourdes Reyes Escogido , Jaime Rivera Morales , Rodolfo Guardado-Mendoza
Aniella G. Ramos-Vázquez , Carlos A. Reyes-Torres , Lilia Castillo-Martínez , Aurora E. Serralde Zúñiga
Olga Lucía Pinzón-Espitia , Juan Mauricio Pardo-Oviedo , Milcíades Ibáñez-Pinilla
Gloria María Novo Martínez , María D. Ballesteros Pomar , Matilde Sierra Vega , Ana Belén García Gallego
Iván Armando Osuna-Padilla , Nadia Carolina Rodríguez-Moguel , Adriana Aguilar-Vargas , Sebastián Rodríguez-Llamazares
Ke Cong , Gu Chunwei
Andrés Luciano Nicolás Martinuzzi , William Manzanares , Eliana Quesada , María Jimena Reberendo , Fernando Baccaro , Irina Aversa , Caludia Elisabeth Kecskes , Lorena Magnífico , Victoria González , Daniela Bolzico , Nancy Baraglia , Priscila Navarrete , Ezequiel Manrique , María Fernanda Cascarón , Ailen Dietrich , Jesica Asparch , Leticia Betiana Peralta , Cayetano Galleti , María Laura Capria , Yamila Lombi , Marian Celia Rodríguez , Camila Ester Luna , Sebastián Pablo Chapela
Mei Jiang , Mengyun Sun , Xuan Zhang , Ruijian Li
Olga Lucía Pinzón-Espitia , Juan Mauricio Pardo-Oviedo , Luisa Fernanda Murcia Soriano
Marta Rodrigues de Carvalho , Beatriz Schmidt Dal Berto , Amelia Maia Rodrigues , Lorena Ohrana Braz Prudente , Edmilson Leal Bastos de Moura
Erica Barreiro Domínguez , Raquel Sánchez Santos , Julio Roberto Ballinas Miranda , Ester Carrera Dacosta , Lara Pérez Corbal , Susana Diz Jueguen , Federico Mallo Ferrer
Yahiel Osorio-Alamillo , Jimena Fuentes-Cummings , Alejandra Ruíz-Barranco , Paulina Bidart-Behar , Patricia Clark , Guillermo Meléndez-Mier , Nallely Bueno Hernández
Hongyan Duan , Jianfeng Zhang , Peng Wang , Jie Zhang , Jianwei Jiang
Background: overweight and obesity have been incre...
Objetivo: el presente estudio tiene como objetivo...