Gestor Editorial

Nuevo Usuario
Nutrición Hospitalaria 03193 / http://dx.doi.org/10.20960/nh.03193
Resumen| PDF (ENGLISH)

Trabajo Original

Interaction between age and vitamin D deficiency in severe COVID-19 infection

Fernando Macaya, Carolina Espejo Paeres, Adrián Valls, Antonio Fernández-Ortiz, Juan González del Castillo, F. Javier Martín-Sánchez, Isabelle Runkle, Miguel Ángel Rubio Herrera

Prepublicado: 2020-09-22
Publicado: 2020-10-13
VOLUMEN 37, NÚM. 5, septiembre-octubre (2020), PAG. 1039-1042

Logo Descargas   Número de descargas: 19642      Logo Visitas   Número de visitas: 16768      Citas   Citas: 28

Compártelo:


Background: coronavirus disease 2019 (COVID-19) can induce an exaggerated inflammatory response. Vitamin D is a key modulator of the immune system. We hypothesized that vitamin D deficiency (VDD) could increase the risk of developing severe COVID-19 infection. Methods: patients with confirmed COVID-19 seen at the emergency department of our hospital with recent measurements of 25(OH)D were recruited. We explored the association of vitamin D deficiency (VDD), defined as 25-hydroxyvitamin D < 20 ng/mL, with a composite of adverse clinical outcomes. Results: we included 80 patients, of which 31 (39 %) presented the endpoint. VDD tended to predict an increased risk of developing severe COVID-19 after adjusting for age, gender, obesity, cardiac disease, and kidney disease [OR 3.2 (95 % CI: 0.9-11.4), p = 0.07]. Age had a negative interaction with the effect of VDD on the composite outcome (p = 0.03), indicating that the effect was more noticeable at younger ages. Furthermore, male gender was associated with VDD and with severe COVID-19 at younger ages. Conclusions: in this retrospective study, vitamin D deficiency showed a signal of association with severe COVID-19 infection. A significant interaction with age was noted, suggesting VDD may have a greater impact in younger patients. These findings should be confirmed in larger, prospective, adequately powered studies.

Palabras Clave: Coronavirus disease 2019. Severe acute respiratory syndrome. Vitamin D deficiency. Angiotensin converting enzyme 2.



Arroyo-Díaz, Juan Antonio, Julve, Josep, Vlacho, Bogdan, Corcoy, Rosa, Ponte, Paola, Román, Eva, Navas-Méndez, Elena, Llauradó, Gemma, Franch-Nadal, Josep, Domingo, Pere, Mauricio, Didac (2021) Previous Vitamin D Supplementation and Morbidity and Mortality Outcomes in People Hospitalised for COVID19: A Cross-Sectional Study. Frontiers in Public Health
Dramé, Moustapha, Cofais, Cécilia, Hentzien, Maxime, Proye, Emeline, Coulibaly, Pécory Souleymane, Demoustier-Tampère, David, Destailleur, Marc-Henri, Lotin, Maxime, Cantagrit, Eléonore, Cebille, Agnès, Desprez, Anne, Blondiau, Fanny, Kanagaratnam, Lukshe, Godaert, Lidvine (2021) Relation between Vitamin D and COVID-19 in Aged People: A Systematic Review. Nutrients
Karonova, Tatiana L., Chernikova, Alena T., Golovatyuk, Ksenia A., Bykova, Ekaterina S., Grant, William B., Kalinina, Olga V., Grineva, Elena N., Shlyakhto, Evgeny V. (2022) Vitamin D Intake May Reduce SARS-CoV-2 Infection Morbidity in Health Care Workers. Nutrients
Efird, Jimmy T., Anderson, Ethan J., Jindal, Charulata, Redding, Thomas S., Thompson, Andrew D., Press, Ashlyn M., Upchurch, Julie, Williams, Christina D., Choi, Yuk Ming, Suzuki, Ayako (2021) The Interaction of Vitamin D and Corticosteroids: A Mortality Analysis of 26,508 Veterans Who Tested Positive for SARS-CoV-2. International Journal of Environmental Research and Public Health
Damascena, Alialdo Dantas, Azevedo, Laylla Mirella Galvão, Oliveira, Tarcio de Almeida, Santana, Jerusa da Mota, Pereira, Marcos (2023) Addendum to vitamin D deficiency aggravates COVID-19: systematic review and meta-analysis. Critical Reviews in Food Science and Nutrition
Fuentes Barría, Héctor, Aguilera Eguía, Raúl Alberto, López Soto, Olga Patricia, Herrera Serna, Brenda Yuliana (2022) Vitamin D supplementation: is it safe and effective for the treatment of COVID-19?. Nutrición Hospitalaria
Karonova, T. L., Andreeva, A. T., Golovatyuk, K. A., Bykova, E. S., Skibo, I. I., Grineva, E. N., Shlyakhto, E. V. (2021) SARS-CoV-2 morbidity depending on vitamin D status. Problems of Endocrinology
Мельниченко, Г. А., Намазова-Баранова, Л. С., Громова, О. А., Драпкина, О. М., Каронова, Т. Л., Куликова, К. С., Крупинова, Ю. А., Лесняк, О. М., Мазурина, Н. В., Панов, А. А., Пигарова, Е. А., Рожинская, Л. Я., Белая, Ж. Е., Руяткина, Л. А., Суплотова, Л. А. (2021) Профилактика и лечение дефицита витамина D: выбор оптимального подхода. Current Pediatrics
Entrenas-Castillo, Marta, Salinero-González, Lourdes, Entrenas-Costa, Luis M., Andújar-Espinosa, Rubén (2022) Calcifediol for Use in Treatment of Respiratory Disease. Nutrients
Dellino, Miriam, Cascardi, Eliano, Vinciguerra, Marina, Lamanna, Bruno, Malvasi, Antonio, Scacco, Salvatore, Acquaviva, Silvia, Pinto, Vincenzo, Di Vagno, Giovanni, Cormio, Gennaro, De Luca, Raffaele, Lafranceschina, Miria, Cazzato, Gerardo, Ingravallo, Giuseppe, Maiorano, Eugenio, Resta, Leonardo, Daniele, Antonella, La Forgia, Daniele (2022) Nutrition as Personalized Medicine against SARS-CoV-2 Infections: Clinical and Oncological Options with a Specific Female Groups Overview. International Journal of Molecular Sciences
Gorman, Shelley, Weller, Richard B. (2020) Investigating the Potential for Ultraviolet Light to Modulate Morbidity and Mortality From COVID-19: A Narrative Review and Update. Frontiers in Cardiovascular Medicine
Pereira, Marcos, Dantas Damascena, Alialdo, Galvão Azevedo, Laylla Mirella, de Almeida Oliveira, Tarcio, da Mota Santana, Jerusa (2022) Vitamin D deficiency aggravates COVID-19: systematic review and meta-analysis. Critical Reviews in Food Science and Nutrition
Camporesi, Giulia, Hernández Payró, Regina, Levy Esses, Tania, Peláez Samperio, María José, Macho González, Adrián, Sánchez-Muniz, Francisco J. (2022) Vitamin D and polymorphisms of VDR and GC genes in the severity and mortality from COVID-19. A systematic review. Nutrición Hospitalaria
Karonova, T. L., Rudenco, E. V., Radaeva, O. A., Chernikova, A. T., Golovatyuk, K. A., Shlyakhto, E. V. (2022) Vitamin D status during the COVID-19 pandemic: the experience of Russia and Belarus. Proceedings of the National Academy of Sciences of Belarus, Medical series
Migliorini, Filippo, Vaishya, Raju, Eschweiler, Jörg, Oliva, Francesco, Hildebrand, Frank, Maffulli, Nicola (2022) Vitamins C and D and COVID-19 Susceptibility, Severity and Progression: An Evidence Based Systematic Review. Medicina
Kaya, Mehmet Onur, Pamukçu, Esra, Yakar, Burkay (2021) The role of vitamin D deficiency on COVID-19: a systematic review and meta-analysis of observational studies. Epidemiology and Health
Gupta, Diviya, Menon, Sahit, Criqui, Michael H., Sun, Bryan K. (2022) Temporal Association of Reduced Serum Vitamin D with COVID-19 Infection: Two Single-Institution Case–Control Studies. Nutrients
Das, Pranta, Samad, Nandeeta, Ahinkorah, Bright Opoku, Hagan, John Elvis, Peprah, Prince, Mohammed, Aliu, Seidu, Abdul-Aziz (2021) Effect of Vitamin D Deficiency on COVID-19 Status: A Systematic Review. COVID
Putra, Harika, Yaswir, Rismawati (2021) Vitamin D Levels among Hospitalized and Non-Hospitalized COVID-19 Patients in Dr. M. Djamil General Hospital Padang. European Journal of Medical and Health Sciences
Mercola, Joseph, Grant, William B., Wagner, Carol L. (2020) Evidence Regarding Vitamin D and Risk of COVID-19 and Its Severity. Nutrients
Ccoicca Casaverde, Bricet Lorena, Paravicino Hoces, Nathali (2021) Vitamin D and its importance for infection with SARS-CoV-2. Nutrición Hospitalaria
Nur, Syafarudin, Sudaryo, Mondastri Korib, Widyasari, Nurul Fajri (2023) Defisiensi Vitamin D sebagai Salah Satu Faktor Risiko Kematian pada Pasien COVID-19: Studi Tinjauan Pustaka. Jurnal Epidemiologi Kesehatan Komunitas
Wang, Min Xian, Gwee, Sylvia Xiao Wei, Pang, Junxiong (2021) Micronutrients Deficiency, Supplementation and Novel Coronavirus Infections—A Systematic Review and Meta-Analysis. Nutrients
Karonova, Tatiana L., Kudryavtsev, Igor V., Golovatyuk, Ksenia A., Aquino, Arthur D., Kalinina, Olga V., Chernikova, Alena T., Zaikova, Ekaterina K., Lebedev, Denis A., Bykova, Ekaterina S., Golovkin, Alexey S., Shlyakhto, Evgeny V. (2022) Vitamin D Status and Immune Response in Hospitalized Patients with Moderate and Severe COVID-19. Pharmaceuticals
Lokshina, Evelina E., Zaytseva, Olga V. (2023) The role of vitamin D in the prevention and treatment of acute respiratory infections in children: A review. Pediatrics. Consilium Medicum
Chiodini, Iacopo, Gatti, Davide, Soranna, Davide, Merlotti, Daniela, Mingiano, Christian, Fassio, Angelo, Adami, Giovanni, Falchetti, Alberto, Eller-Vainicher, Cristina, Rossini, Maurizio, Persani, Luca, Zambon, Antonella, Gennari, Luigi (2021) Vitamin D Status and SARS-CoV-2 Infection and COVID-19 Clinical Outcomes. Frontiers in Public Health
Efird, Jimmy T., Anderson, Ethan J., Jindal, Charulata, Suzuki, Ayako (2022) Interaction of Vitamin D and Corticosteroid Use in Hospitalized COVID-19 Patients: A Potential Explanation for Inconsistent Findings in the Literature. Current Pharmaceutical Design
Tizenberg, Boris N., Brenner, Lisa A., Lowry, Christopher A., Okusaga, Olaoluwa O., Benavides, David R., Hoisington, Andrew J., Benros, Michael E., Stiller, John W., Kessler, Ronald C., Postolache, Teodor T. (2021) Biological and Psychological Factors Determining Neuropsychiatric Outcomes in COVID-19. Current Psychiatry Reports
Gombart AF, Pierre A, Maggini S. A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection. Nutrients 2020;12:236.
DOI: 10.3390/nu12010236
Grant WB, Lahore H, McDonnell SL, Baggerly CA, French CB, Aliano JL, et al. Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths. Nutrients 2020;12:988.
DOI: 10.3390/nu12040988
Xu J, Yang J, Chen J, Luo Q, Zhang Q, Zhang H. Vitamin D alleviates lipopolysaccharide-induced acute lung injury via regulation of the renin-angiotensin system. Molecular Medicine Reports 2017;16:7432-8.
DOI: 10.3892/mmr.2017.7546
Amrein K, Scherkl M, Hoffmann M, Neuwersch-Sommeregger S, Köstenberger M, Tmava Berisha A, et al. Vitamin D deficiency 2.0: an update on the current status worldwide. European Journal of Clinical Nutrition 2020;1-16.
DOI: 10.1038/s41430-020-0558-y
Manios Y, Moschonis G, Lambrinou C-P, Tsoutsoulopoulou K, Binou P, Karachaliou A, et al. A systematic review of vitamin D status in southern European countries. European Journal of Nutrition 2018;57:2001-36.
DOI: 10.1007/s00394-017-1564-2
González-Molero I, Morcillo S, Valdés S, Pérez-Valero V, Botas P, Delgado E, et al. Vitamin D deficiency in Spain: a population-based cohort study. European Journal of Clinical Nutrition 2011;65:321-8.
DOI: 10.1038/ejcn.2010.265
Dancer RCA, Parekh D, Lax S, D’Souza V, Zheng S, Bassford CR, et al. Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS). Thorax 2015;70:617-24.
DOI: 10.1136/thoraxjnl-2014-206680
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395:497-506.
DOI: 10.1016/S0140-6736(20)30183-5
Sattar Naveed, McInnes Iain B., McMurray John J. V. Obesity a Risk Factor for Severe COVID-19 Infection: Multiple Potential Mechanisms. Circulation [Internet] [cited 2020 Apr 24]. Available from: https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.120.047659
DOI: 10.1161/CIRCULATIONAHA.120.047659
Liang S, Cai J, Li Y, Yang R. 1,25‑Dihydroxy‑Vitamin D3 induces macrophage polarization to M2 by upregulating T‑cell Ig‑mucin‑3 expression. Mol Med Rep 2019;19:3707-13.
DOI: 10.3892/mmr.2019.10047
Kong J, Zhu X, Shi Y, Liu T, Chen Y, Bhan I, et al. VDR Attenuates Acute Lung Injury by Blocking Ang-2-Tie-2 Pathway and Renin-Angiotensin System. Molecular Endocrinology 2013;27:2116-25.
DOI: 10.1210/me.2013-1146
Vaduganathan M, Vardeny O, Michel T, McMurray JJV, Pfeffer MA, Solomon SD. Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19. New England Journal of Medicine 2020;382:1653-9.
DOI: 10.1056/NEJMsr2005760
Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, et al. Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature 2005;436:112-6.
DOI: 10.1038/nature03712
D’Avolio A, Avataneo V, Manca A, Cusato J, De Nicolò A, Lucchini R, et al. 25-Hydroxyvitamin D Concentrations Are Lower in Patients with Positive PCR for SARS-CoV-2. Nutrients 2020;12.
DOI: 10.3390/nu12051359
Ilie PC, Stefanescu S, Smith L. The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Aging Clinical and Experimental Research [Internet] 2020 [cited 2020 May 17]. Available from: http://link.springer.com/10.1007/s40520-020-01570-8
DOI: 10.1007/s40520-020-01570-8
Guo Y-R, Cao Q-D, Hong Z-S, Tan Y-Y, Chen S-D, Jin H-J, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status. Military Medical Research [Internet] 2020 [cited 2020 May 4]. Available from: https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-020-00240-0
DOI: 10.1186/s40779-020-00240-0
La Vignera S, Cannarella R, Condorelli RA, Torre F, Aversa A, Calogero AE. Sex-Specific SARS-CoV-2 Mortality: Among Hormone-Modulated ACE2 Expression, Risk of Venous Thromboembolism and Hypovitaminosis D. International Journal of Molecular Sciences 2020;21:2948.
DOI: 10.3390/ijms21082948
Waldhoer T, Endler G, Yang L, Haidinger G, Wagner O, Marculescu R. Vitamin D deficiency, overall and cause-specific mortality: the impact of age. Revue d’Épidémiologie et de Santé Publique 2018;66:S271.
DOI: 10.1016/j.respe.2018.05.092
Oh S-J, Lee JK, Shin OS. Aging and the Immune System: the Impact of Immunosenescence on Viral Infection, Immunity and Vaccine Immunogenicity. Immune Network [Internet] 2019 [cited 2020 Apr 26]. Available from: https://synapse.koreamed.org/DOIx.php?id=10.4110/in.2019.19.e37
DOI: 10.4110/in.2019.19.e37
Varsavsky M, Rozas Moreno P, Becerra Fernández A, Luque Fernández I, Quesada Gómez JM, Ávila Rubio V, et al. Recomendaciones de vitamina D para la población general. Endocrinología, Diabetes y Nutrición 2017;64:7-14.
DOI: 10.1016/j.endinu.2016.11.002

Artículos Relacionados:

Revisión: Relationship between vitamin D deficiency and both gestational and postpartum depression

Amanda Ribamar , Beatriz Almeida , Andressa Soares , Beatriz Peniche , Patrícia Jesus , Sabrina Pereira da Cruz , Andréa Ramalho

Publicado: 2019-11-18 / http://dx.doi.org/10.20960/nh.02953
Resumen | PDF

Editorial: La infección por coronavirus SARS-CoV-2 y su relación con el estado nutricional

Pablo Jesús Remón Ruiz , Pedro P. García Luna

Publicado: 2020-05-27 / http://dx.doi.org/10.20960/nh.03184
Resumen | PDF

Revisión: Manejo nutricional del paciente hospitalizado críticamente enfermo con COVID-19. Una revisión narrativa

Luis Eduardo González-Salazar , Martha Guevara-Cruz , Karla Guadalupe Hernández-Gómez , Aurora E. Serralde-Zúñiga

Publicado: 2020-05-25 / http://dx.doi.org/10.20960/nh.03180
Resumen | PDF

Trabajo Original: Effect of the COVID-19 quarantine on body mass among combat sports athletes

Tomás Herrera-Valenzuela , José Jairo Narrea Vargas , Rodrigo Merlo , Pablo Antonio Valdés-Badilla , Carolina Pardo-Tamayo , Emerson Franchini

Publicado: 2020-06-09 / http://dx.doi.org/10.20960/nh.03207
Resumen | PDF

Trabajo Original: Comparación de las recomendaciones de expertos sobre nutrición clínica en pacientes hospitalizados con COVID-19

Jéssica Martínez Rodríguez , Maria Roca Fontbona

Publicado: 2020-05-29 / http://dx.doi.org/10.20960/nh.03194
Resumen | PDF

Trabajo Original: Effect of lockdown for COVID-19 on self-reported body weight gain in a sample of obese patients

Daniel de Luis Román , Olatz Izaola Jáuregui , David Primo Martín , Emilia Gómez Hoyos , Beatriz Torres , Juan José López

Publicado: 2020-08-17 / http://dx.doi.org/10.20960/nh.03307
Resumen | PDF

Trabajo Original: Hábitos alimentarios en la población gallega durante el confinamiento por la COVID-19

Laura Isabel Sinisterra Loaiza , Beatriz Vázquez Belda , José Manuel Miranda López , Alberto Cepeda , Alejandra Cardelle Cobas

Publicado: 2020-06-12 / http://dx.doi.org/10.20960/nh.03213
Resumen | PDF

Carta Editor: Confinamiento domiciliario por COVID-19 y ganancia ponderal en escolares y adolescentes

Teodoro Durá-Travé

Publicado: 2020-10-30 / http://dx.doi.org/10.20960/nh.03417
Resumen | PDF

Artículo Especial: Physical activity recommendations during the COVID-19 pandemic: a practical approach for different target groups

Salvador Baena Morales , Pedro Tauler Riera , Antonio Aguiló Pons , Olalla García Taibo

Publicado: 2020-09-23 / http://dx.doi.org/10.20960/nh.03363
Resumen | PDF

Grupo de Trabajo SENPE: Pandemia de COVID y respuesta de la nutrición clínica en España: resultados de una encuesta nacional

Tomás Martín Folgueras , Néstor Benítez-Brito , Alfonso Vidal-Casariego , Luis Miguel Luengo Pérez , José A. Irles-Rocamora

Publicado: 2020-09-28 / http://dx.doi.org/10.20960/nh.03370
Resumen | PDF

Carta Editor: The psychological impact of preexisting mental and physical health during the COVID-19 pandemic

Marina Vukotic , Dragan Krivokapic , Marija Bubanja , Miodrag Zarubica , Srdjan Redzepagic

Publicado: 2020-11-27 / http://dx.doi.org/10.20960/nh.03456
Resumen | PDF

Editorial: El rincón de los editores. 2020: el año de la pandemia por COVID-19

José Manuel Moreno Villares , Gabriel Olveira Fuster

Publicado: 2021-01-11 / http://dx.doi.org/10.20960/nh.03508
Resumen | PDF

Revisión: Hipótesis sobre las conexiones entre COVID-19 severo en niños y nutrición: una revisión narrativa

Ximena León-Lara , Ariana Vargas-Castillo , Azalia Avila-Nava , Martha Guevara-Cruz , Aurora E Serralde Zúñiga , Isabel Medina-Vera

Publicado: 2020-11-25 / http://dx.doi.org/10.20960/nh.03452
Resumen | PDF

Trabajo Original: Evolución de la infección por SARS-CoV-2 en función del estado metabólico previo del paciente

María Martínez Urbistondo , Alberto Mora Vargas , Esther Expósito Palomo , María Aparicio de Miguel , Raquel Castejón Díaz , Lidia Daimiel , Óscar Omar Ramos López , Rodrigo San Cristóbal , J Alfredo Martínez , Juan Antonio Vargas Núñez

Publicado: 2020-12-05 / http://dx.doi.org/10.20960/nh.03469
Resumen | PDF

Trabajo Original: High nutritional risk using NUTRIC-Score is associated with worse outcomes in COVID-19 critically ill patients

Iván Armando Osuna-Padilla , Nadia Carolina Rodríguez-Moguel , Adriana Aguilar-Vargas , Sebastián Rodríguez-Llamazares

Publicado: 2020-11-17 / http://dx.doi.org/10.20960/nh.03440
Resumen | PDF

Carta Editor: Level of active lifestyle and exercise approach among students of the University of Novi Pazar during the COVID-19 pandemic

Dragan Bacovic , Pavle Malovic , Marija Bubanja

Publicado: 2021-04-19 / http://dx.doi.org/10.20960/nh.03658
Resumen | PDF

Carta Editor: Vitamina D y su importancia en la infección por SARS-CoV-2

Briceth Lorena Ccoicca Casaverde , Nathali Paravicino Hoces

Publicado: 2021-05-25 / http://dx.doi.org/10.20960/nh.03715
Resumen | PDF

Trabajo Original: Déficit de vitamina D en una población pediátrica sana. La importancia de una adecuada profilaxis

Inés Martínez Redondo , Ruth García Romero , Pilar Calmarza , Antonio de Arriba Muñoz , Diana Martínez-Redondo , Alejandro Sanz Paris

Publicado: 2021-03-07 / http://dx.doi.org/10.20960/nh.03606
Resumen | PDF

Trabajo Original: Resultados de una encuesta dirigida a dietistas-nutricionistas sobre la gestión de los equipos de nutrición clínica durante la pandemia de COVID-19 en centros hospitalarios de Cataluña

Jéssica Martínez Rodríguez , Maria Roca Fontbona

Publicado: 2021-06-30 / http://dx.doi.org/10.20960/nh.03759
Resumen | PDF

Trabajo Original: Nutritional status in patients with COVID-19 and cancer: the experience of the National Cancer Institute in Mexico

Dana Aline Pérez-Camargo , Gaspar Vargas Gutiérrez , Mónica M. Rivera-Franco , Anabel Labana Ramírez , Monserrat Castro Herrera , Víctor Itaí Urbalejo-Ceniceros , Erika Thalia Copca-Mendoza , Osiris Loyola Serrano , Eréndira Baltazar Luna , Abelardo Meneses García , Ángel Herrera Gómez , Aarón González Enciso , María de la Luz Sevilla-González

Publicado: 2021-05-05 / http://dx.doi.org/10.20960/nh.03683
Resumen | PDF

Trabajo Original: Nutritional risk and clinical outcomes in critically ill adult patients with COVID-19

Andrés Luciano Nicolás Martinuzzi , William Manzanares , Eliana Quesada , María Jimena Reberendo , Fernando Baccaro , Irina Aversa , Caludia Elisabeth Kecskes , Lorena Magnífico , Victoria González , Daniela Bolzico , Nancy Baraglia , Priscila Navarrete , Ezequiel Manrique , María Fernanda Cascarón , Ailen Dietrich , Jesica Asparch , Leticia Betiana Peralta , Cayetano Galleti , María Laura Capria , Yamila Lombi , Marian Celia Rodríguez , Camila Ester Luna , Sebastián Pablo Chapela

Publicado: 2021-06-23 / http://dx.doi.org/10.20960/nh.03749
Resumen | PDF

Trabajo Original: Riesgo nutricional y desenlaces clínicos en pacientes con diagnóstico de COVID-19 en una red hospitalaria de alta complejidad

Olga Lucía Pinzón-Espitia , Juan Mauricio Pardo-Oviedo , Luisa Fernanda Murcia Soriano

Publicado: 2021-06-11 / http://dx.doi.org/10.20960/nh.03738
Resumen | PDF

Trabajo Original: Diabetes might not be a risk factor for worse prognosis among hospitalized patients due to COVID-19 in a Mediterranean area

Joana Nicolau , Pilar Sanchís , Keyla Dotres Fallat , Andrea Romano , Irene Rodríguez , Lluís Masmiquel

Publicado: 2021-08-31 / http://dx.doi.org/10.20960/nh.03855
Resumen | PDF

Trabajo Original: Efecto de la COVID-19 en la prescripción dietoterapéutica durante el primer semestre de 2020 en la Comunidad de Madrid

Carolina Luque , Ángel Mataix , Ángel Candela , Nilda Martínez , José Luis Calleja , Rosario Pintor , José Ignacio Botella Carretero , Francisco Arrieta Blanco

Publicado: 2021-06-29 / http://dx.doi.org/10.20960/nh.03758
Resumen | PDF

Nota Clínica: Tetania secundaria a raquitismo carencial

Publicado: 2021-09-28 / http://dx.doi.org/
Resumen | PDF

Trabajo Original: Effect of immunonutrition on serum levels of C-reactive protein and lymphocytes in patients with COVID-19: a randomized, controlled, double-blind clinical trial

Rodrigo Fernandes Weyll Pimentel , Arthur Pinto Silva , Amália Ivine Costa Santana , Douglas de Souza e Silva , Mariângela de Souza Ramos , Márcio Costa de Souza , Vivian Marques Miguel Suen , Isolda Padro de Negreiros Nogueira Maduro , Durval Ribas Filho , Argemiro D’Oliveira Júnior , Dandara Almeida Reis da Silva , Julita Maria Freitas Coelho , Antonio Marcos Tosoli Gomes , Paulo Roberto Lima Machado , Magno Conceição das Merces

Publicado: 2021-08-26 / http://dx.doi.org/10.20960/nh.03847
Resumen | PDF

Trabajo Original: Vitamin D levels and bone turnover markers are not related to non-alcoholic fatty liver disease in severely obese patients

Publicado: 2021-11-17 / http://dx.doi.org/
Resumen | PDF

Trabajo Original: Severe COVID-19 patients have severe vitamin D deficiency in Northeast Mexico

Edgar Paolo Rodríguez Vidales , Denise Garza Carrillo , Ana María Salinas Martínez , Olivia Abigail Robles Rodríguez , Roberto Montes de Oca Luna , Consuelo Treviño Garza , Alma Rosa Marroquín Escamilla , Manuel Enrique de la O-Cavazos

Publicado: 2021-06-08 / http://dx.doi.org/10.20960/nh.03731
Resumen | PDF

Carta Editor: Assessment level of physical activity of young school children in Montenegro, using the PAQ-C questionnaire, during the COVID-19 pandemic

Dragan Bacovic

Publicado: 2021-12-04 / http://dx.doi.org/10.20960/nh.03986
Resumen | PDF

Carta Editor: Suplementación con vitamina D: ¿es segura y eficaz para el tratamiento de la COVID-19?

Héctor Fuentes-Barría , Raúl Alberto Aguilera-Eguía , Catalina González Wong , Olga Patricia López Soto , Brenda Yuliana Herrera Serna

Publicado: 2021-12-28 / http://dx.doi.org/10.20960/nh.04020
Resumen | PDF

Trabajo Original: Cambios en el comportamiento alimentario de personas adultas con elevado nivel académico durante las diferentes etapas del confinamiento domiciliario por COVID-19 en Iberoamérica

Luisa Muñoz Salvador , Mercedes Briones Urbano , Yago Pérez

Publicado: 2021-12-28 / http://dx.doi.org/10.20960/nh.04018
Resumen | PDF

Carta Editor: Estado nutricional y niveles de ansiedad durante la pandemia de COVID-19

Héctor Fuentes-Barría , Raúl Alberto Aguilera-Eguía , Luis Soto Jara , Catalina González Wong

Publicado: 2022-02-17 / http://dx.doi.org/10.20960/nh.04086
Resumen | PDF

Nota Clínica: Beau’s line in COVID-19 after a long ICU stay

Jessica Alves de Paula , Claudio Luciano Franck , Sandra Regina Justino , Luíza Silva Leite , Odery Ramos Junior , Estela Iraci Rabito

Publicado: 2022-03-24 / http://dx.doi.org/10.20960/nh.04131
Resumen | PDF

Carta Editor: Results of lifestyle during confinement COVID-19 in schoolchildren aged 8 to 12 years

Luis Alberto Flores Olivares , Liliana Aracely Enriquez-del Castillo , Leslie Michelle González Cano , Estefania Quintana Mendias , Natanael Cervantes Hernández

Publicado: 2022-06-06 / http://dx.doi.org/10.20960/nh.04272
Resumen | PDF

Carta Editor: La necesidad de un programa multidimensional para pacientes con obesidad, como medida preventiva ante una nueva ola de Covid-19 en Chile

Michel Alberto Garat Escudero , Ángel Roco-Videla

Publicado: 2022-06-09 / http://dx.doi.org/10.20960/nh.04280
Resumen | PDF

Carta Editor: Salud mental en niños y adolescentes como factor agravante en la pandemia del Covid-19

Michel Alberto Garat Escudero , Ángel Roco-Videla

Publicado: 2022-06-16 / http://dx.doi.org/10.20960/nh.04290
Resumen | PDF

Trabajo Original: Calidad de la alimentación en preescolares y escolares en Chile durante la pandemia de COVID-19

Nelson Hun Gamboa , Massiel Salazar , Sebastián Aliste , Camilo Aguilera , María Elvira Cárdenas

Publicado: 2022-08-01 / http://dx.doi.org/10.20960/nh.04383
Resumen | PDF

Revisión: Vitamina D y polimorfismos de los genes VDR y GC en la severidad y mortalidad por COVID-19. Una revisión sistemática

Giulia Camporesi , Regina Hernández Payró , Tania Levy Esses , María José Peláez Samperio , Adrián Macho González , Francisco J. Sánchez-Muniz

Publicado: 2022-06-23 / http://dx.doi.org/10.20960/nh.04299
Resumen | PDF

Trabajo Original: Risk of vitamin D deficit in asthmatic children hospitalized in the north area of Santiago

María Elena Herrera , Gerardo Weisstaub , Ana María Herrera Gana , Ricardo Pinto

Publicado: 2022-05-21 / http://dx.doi.org/10.20960/nh.04249
Resumen | PDF

Trabajo Original: Evolución de la dieta y la actividad física de los estudiantes universitarios tras la pandemia de COVID-19

Almudena Tárraga Marcos , Julio Antonio Carbayo Herencia , Josefa Maria Panisello Royo , José Francisco López Gil , Loreto Tárraga Marcos , Pedro Juan Tárraga López

Publicado: 2022-09-01 / http://dx.doi.org/10.20960/nh.04420
Resumen | PDF

Trabajo Original: Inequalities in the association between adherence to the Mediterranean diet and physical fitness in the young population during the COVID-19 lockdown

Javier Brazo Sayavera , Inácio Crochemore-Silva , Bruno Bizzozero Peroni , Noelia González-Gálvez , Edina Maria de Camargo , José Francisco López-Gil

Publicado: 2022-05-04 / http://dx.doi.org/10.20960/nh.04225
Resumen | PDF

Revisión: Influencia de la dieta en el riesgo de infección y de gravedad de la COVID-19: una revisión sistemática

Ester Leno-Durán , Marcos Micha Mabale , Marina García-Pérez , Aurora Bueno-Cavanillas , Rocío Barrios-Rodríguez , Pilar Requena

Publicado: 2022-09-20 / http://dx.doi.org/10.20960/nh.04448
Resumen | PDF

Trabajo Original: Feeding intolerance during prolonged prone position in overweight and obese patients with severe COVID-19

Iván Armando Osuna-Padilla , Nadia Carolina Rodríguez-Moguel , Laurie Abril López-Orduña , Ana Lucía Gómez-Rodríguez , Alan García-Grimaldo , Sebastián Rodríguez-Llamazares , Ismael Maldonado-Beltrán , Martín Armando Ríos-Ayala , Carmen Margarita Hernández-Cárdenas

Publicado: 2022-11-28 / http://dx.doi.org/10.20960/nh.04553
Resumen | PDF

Trabajo Original: The CONUT score predicts the length of hospital stay and the risk of long COVID

Zi-Wen Zhao , Qin Chen , Xin-Tao Zhang , Yu-Kun Luo

Publicado: 2023-02-22 / http://dx.doi.org/10.20960/nh.04656
Resumen | PDF

Trabajo Original: Physical activity as a mediator of the association of body mass index change with anxiety/depression symptoms in Brazilian adults during COVID-19

Edina Maria de Camargo , José Francisco López Gil , Cristiane Galvao Costa , Pedro Juan Tárraga López , Wagner de Campos , Sergio Gregorio da Silva Silva

Publicado: 2023-04-02 / http://dx.doi.org/10.20960/nh.04716
Resumen | PDF

Trabajo Original: Lifestyles of 2- to 11-year-old children during the COVID-19 pandemic

Erika Mayorga-Borbolla , Danae Gabriela Valenzuela-Bravo , María del Carmen Morales-Ruán , Ignacio Méndez-Gómez Humarán , Teresa Shamah-Levy

Publicado: 2023-04-15 / http://dx.doi.org/10.20960/nh.04738
Resumen | PDF

Trabajo Original: It is not just about prescription. A cohort study of the impact of enteral nutrition on mortality of hospitalized patients with COVID-19

Adriana Flores-López , Gabriela Quiroz-Olguin , Alejandro Gabriel González-Garay , Aurora E. Serralde-Zúñiga

Publicado: 2023-06-22 / http://dx.doi.org/10.20960/nh.04828
Resumen | PDF

Trabajo Original: Health habits during lockdown for COVID-19 in Spain and its effect on weight

José I. Baile , María J. González-Calderón , MARIA FRENZI RABITO ALCON , Eva Izquierdo Sotorrío

Publicado: 2023-04-18 / http://dx.doi.org/10.20960/nh.04740
Resumen | PDF

Artículos más populares

Revisión: Bebidas de soja y salud femenina. Revisión de la evidencia y opinión de expertos

Las bebidas vegetales de soja constituyen una alte...

Publicado: 2022-07-25
Resumen | PDF

Trabajo Original: Experience with the management of patients requiring home enteral nutrition in routine clinical practice in Spain: the ECONES study

Introduction: enteral nutrition is an effective me...

Publicado: 2023-02-09
Resumen | PDF

Revisión: La dieta como fuente de sulfuro de hidrógeno y sus efectos en la salud y la enfermedad

Conocido originalmente por sus efectos deletéreos...

Publicado: 2022-09-28
Resumen | PDF

Editado en Madrid por:
Diseño y Desarrollo web Im3diA comunicación

Una cookie o galleta informática es un pequeño archivo de información que se guarda en su navegador cada vez que visita nuestra página web. La utilidad de las cookies es guardar el historial de su actividad en nuestra página web, de manera que, cuando la visite nuevamente, ésta pueda identificarle y configurar el contenido de la misma en base a sus hábitos de navegación, identidad y preferencias. Las cookies pueden ser aceptadas, rechazadas, bloqueadas y borradas, según desee. Ello podrá hacerlo mediante las opciones disponibles en la presente ventana o a través de la configuración de su navegador, según el caso. En caso de que rechace las cookies no podremos asegurarle el correcto funcionamiento de las distintas funcionalidades de nuestra página web. Más información en el apartado “POLÍTICA DE COOKIES” de nuestra página web.

Rechazar