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Nutrición Hospitalaria 05681 / http://dx.doi.org/10.20960/nh.05681
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Trabajo Original

Effect of low-sodium, potassium-rich salt based on the Chinese modified DASH diet on home blood pressure monitoring in patients with hypertension and type 2 diabetes: a clinical trial

Li Zhao, Jiaxian An, Wenjun Luo, Ying Mei, Xiaoqing Bu, Shili Xian, Pingping Yu, Huang Yao, Lihong Mu

Prepublicado: 2025-06-04

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Objective: to investigate the impact and safety of Chinese Modified Dietary Approaches to Stop Hypertension (CM-DASH) combined with sodium-restricted formula salts on home blood pressure monitoring (HBPM) in patients with hypertension and type 2 diabetes. Design: employing a semi-open randomized, controlled, single-blind trial, patients were allocated into four groups—Group A (control), Group B (52 % salt), Group C (23 % salt), and Group D (meal packs)—for an eight-week dietary intervention. Throughout the intervention, patients self-measured their blood pressure daily and were followed up weekly. Additionally, 24-hour urine was performed at baseline, week 4, and the end of the intervention. Results: of the 132 initial participants, only two were lost to follow-up. Following an 8-week intervention, blood pressure exhibited a downward trend across all four subject groups (p < 0.05). Both HSBP and HDBP exhibited a more pronounced decrease in group B compared to group A. HSBP decreased the most in group D (-13.06, 95 % CI: -18.84 to 7.64, p < 0.001). The 24-hour urinary Na/K ratios significantly dropped in low-sodium salt participants (p < 0.001). Nevertheless, the differences between the groups were not statistically significant. No serious adverse events were reported throughout the trial. Conclusions: this study's preliminary findings indicate that the CM-DASH dietary pattern combined with 23 % and 52 % sodium-limited formula salts has a beneficial effect on home blood pressure in hypertensive and type 2 diabetes patients. Additionally, it improves patients’ urinary sodium and potassium levels and demonstrates safety. However, more studies are needed for validation.

Palabras Clave: Hypertension. Type 2 diabetes. DASH. 23 % sodium-restricted formula salts. 52 % sodium-restricted formula salts. Home blood pressure.



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Publicado: 2022-09-28 / http://dx.doi.org/10.20960/nh.04471
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Trabajo Original: Effect of 23 % low-sodium salt applied to Chinese modified DASH diet on cerebrovascular function in patients with hypertension and type 2 diabetes: a pilot study

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Trabajo Original: Effect of low-sodium salt applied to Chinese modified DASH diet on arterial stiffness in older patients with hypertension and type 2 diabetes

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Publicado: 2023-01-31 / http://dx.doi.org/10.20960/nh.04622
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Carta Editor: Relationship between fermented dairy consumption, gut microbiota and type 2 diabetes

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Publicado: 2024-07-19 / http://dx.doi.org/10.20960/nh.05435
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Revisión: Patrones dietéticos asociados a la obesidad y a sus comorbilidades

María Dolores Salas-González , Viviana Loria-Kohen , África Peral-Suárez , Alfredo Trabado-Fernández , Liliana Guadalupe González-Rodríguez

Publicado: 2024-07-29 / http://dx.doi.org/10.20960/nh.05457
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Trabajo Original: Consumption of ultra-processed foods raises the possibility of cardiovascular disease – A meta-analysis

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Publicado: 2024-09-10 / http://dx.doi.org/10.20960/nh.05521
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Trabajo Original: Enfermedad hepática esteatósica asociada a disfunción metabólica (MASLD) y fibrosis hepática. Propuesta de score APRI+FIB4+NFS

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Publicado: 2024-04-02 / http://dx.doi.org/10.20960/nh.05252
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