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Iodine levels are associated with oxidative stress and antioxidant status in pregnant women with hypertensive disease

Sergio Cuellar-rufino, Mónica Navarro-meza, Pablo García-solís, Irene Xochihua-rosas, Omar Arroyo-helguera

VOLUMEN 34, NÚM. 3, mayo-junio (2017), PAG. 661-666

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Background: The antioxidant function of iodine and iodine deficiency as a risk factor of preeclampsia have been previously reported.Aim: To analyze the association between iodine deficiency, oxidative stress and antioxidant status with hypertensive disease of pregnancy (HPD).Method: Fifty-seven pregnant women were recruited in the last trimester of pregnancy; 20 were diagnosed with hypertensive disease (HPD) of pregnancy and 37 were normotensive pregnant women. Urinary iodine concentration (UIC), TSH, free T4 (fT4), total antioxidant status (FRP), superoxide dismutase (SOD), catalase (CAT), and oxidative stress (TBARS) were evaluated by colorimetric methods. Results: UIC median for all pregnant women was 151.9 µg/l. The UIC for pregnant women with HPD was 50-149 µg/l, compared to 150-249 µg/l in normotensive women. No significant differences in levels of TSH and fT4 in normotensive pregnant compared with HPD women were found. Pregnant women with HPD had significant high levels of TBARS, and significant low levels of FRP, SOD, CAT and UIC compared to normotensive pregnant. In addition, pregnant women with optimal levels of UIC had a higher SOD activity (r = 0.354, p = 0.011), while iodine deficiency was associated with HPD (r = -0,281, p = 0.039). Similarly, pregnant women with HPD had a significant negative association with SOD activity (r = -0.702, p = 0.005), CAT (r = -0.409, p = 0.002), and FRP (r = -0.624, p = 0.003), and a positive association with TBARS (r = 0.744, p = 0.001).Conclusion: Iodine contributes to redox balance during pregnancy; its deficiency is associated with HPD. This study shows the importance of iodine during pregnancy.

Palabras Clave: Iodine deficiency. Pregnancy-induced hypertension. Oxidative stress. Antioxidant status.



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Trabajo Original: Mineral and/or milk supplementation of fruit beverages helps in the prevention of H2O2-induced oxidative stress in Caco-2 cells

Publicado: 2021-06-25 / http://dx.doi.org/
Resumen | PDF

Trabajo Original: Dietary intake and oxidative stress in breast cancer: before and after treatments

Publicado: 2021-06-28 / http://dx.doi.org/
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Trabajo Original: Efecto de la suplementación con antioxidantes sobre el estrés oxidativo y la calidad de vida durante el tratamiento oncológico en pacientes con cáncer cérvico uterino

Publicado: 2021-06-28 / http://dx.doi.org/
Resumen | PDF

Revisión: Meta-análisis del papel del licopeno en la diabetes mellitus tipo 2

Publicado: 2021-07-02 / http://dx.doi.org/
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Trabajo Original: Problemática nutricional en fumadores y fumadores pasivos

Rosa M. Ortega , Ana Isabel Jiménez-Ortega , Rosa María Martínez García , Ana María Lorenzo-Mora , María del Carmen Lozano-Estevan

Publicado: 2021-07-20 / http://dx.doi.org/10.20960/nh.03794
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Revisión: The role of hyperglycemia in the induction of oxidative stress and inflammatory process

Publicado: 2021-10-04 / http://dx.doi.org/
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Trabajo Original: Enzyme activity of superoxide dismutase and zincemia in women with preeclampsia

Publicado: 2021-10-19 / http://dx.doi.org/
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Trabajo Original: Estrés oxidativo; estudio comparativo entre un grupo de población normal y un grupo de población obesa mórbida

Publicado: 2021-10-25 / http://dx.doi.org/
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Trabajo Original: Relación del estrés oxidativo y la pérdida de peso obtenida en pacientes obesos mórbidos mediante cirugía bariátrica con la técnica del cruce duodenal

Publicado: 2021-10-26 / http://dx.doi.org/
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Trabajo Original: Peroxidación de lípidos y la respuesta del sistema de defensa antioxidante en el diabético tipo 2 obeso en comparación al diabético tipo 2 sin obesidad

Publicado: 2021-10-28 / http://dx.doi.org/
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Trabajo Original: Prevalence of metilentetrahidrofolate reductase C677T polymorphism, consumption of vitamins B6, B9, B12 and determination of lipidic hydroperoxides in obese and normal weight Mexican population

Publicado: 2021-10-29 / http://dx.doi.org/
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Revisión: Micronutrients influencing the immune response in leprosy

Publicado: 2021-11-02 / http://dx.doi.org/
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Trabajo Original: Interaction between mercury (Hg), arsenic (As) and selenium (Se) affects the activity of glutathione S-transferase in breast milk; possible relationship with fish and shellfish intake

Publicado: 2021-11-04 / http://dx.doi.org/
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Trabajo Original: Defensas antioxidantes en leche materna en relación al número de gestas y a la edad de las madres

Publicado: 2021-11-08 / http://dx.doi.org/
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Trabajo Original: Influence of magnesium on biochemical parameters of iron and oxidative stress in patients with type 2 diabetes

Publicado: 2021-11-08 / http://dx.doi.org/
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Trabajo Original: Hypoalbuminemia and oxidative stress in patients on renal hemodialysis program

Publicado: 2021-11-15 / http://dx.doi.org/
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Trabajo Original: Indicadores de estrés oxidativo en suero y comportamiento alimentario en adultos de una zona rural de Jalisco, México

Publicado: 2021-11-18 / http://dx.doi.org/
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Trabajo Original: High-protein diet induces oxidative stress in rat brain: protective action of high-intensity exercise against lipid peroxidation

Publicado: 2021-11-25 / http://dx.doi.org/
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Trabajo Original: Glycemic Control and Oxidative Stress Markers and their relationship with the Thioredoxin Interacting Protein (TXNIP) gene in Type 2 Diabetic patients

Publicado: 2021-11-25 / http://dx.doi.org/
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Trabajo Original: Effect of computer radiation on weight and oxidant-antioxidant status of mice

Publicado: 2021-11-25 / http://dx.doi.org/
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Trabajo Original: Factores que inciden el daño oxidativo en niños con obesidad: estudio piloto

Publicado: 2021-11-26 / http://dx.doi.org/
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Trabajo Original: Purine nucleoside phosphorylase and the enzymatic antioxidant defense system in breast milk from women with different levels of arsenic exposure

Publicado: 2021-11-30 / http://dx.doi.org/
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Trabajo Original: Reduction of serum advanced glycation end-products with a low calorie Mediterranean diet

Publicado: 2021-11-30 / http://dx.doi.org/
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Trabajo Original: Fish oil and vitamin E change lipid profiles and anti-LDL-antibodies in two different ethnic groups of women transitioning through menopause

Publicado: 2021-12-01 / http://dx.doi.org/
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Trabajo Original: Effect of long term intake of white tea on acute oxidative stress in rats

Publicado: 2022-01-11 / http://dx.doi.org/
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Trabajo Original: Relationship between zincemia, superoxide dismutase activity and marker of oxidative stress in women with breast cancer

Publicado: 2022-01-12 / http://dx.doi.org/
Resumen | PDF

Revisión: Potencial antioxidante de la miel de Melipona beecheii y su relación con la salud: una revisión

Publicado: 2022-01-19 / http://dx.doi.org/
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Trabajo Original: Glutathione peroxidase-1 Pro200Leu polymorphism (rs1050450) is associated with morbid obesity independently of the presence of prediabetes or diabetes in women from Central Mexico

Publicado: 2022-01-19 / http://dx.doi.org/
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Trabajo Original: Dietary fish oil increases catalase activity in patients with probable Alzheimer’s disease

Blanca M. G. Torres-Mendoza , Genaro Gabriel Ortiz , Lorenzo Sánchez-Romero , Daniela L. C. Delgado-Lara , María T. García Martínez , Mario-Alberto Mireles-Ramírez , José Antonio Cruz Serrano , Fermín Paul Pacheco Moisés

Publicado: 2022-04-08 / http://dx.doi.org/10.20960/nh.04153
Resumen | PDF

Trabajo Original: Vitamin D levels and their association with oxidative stress and inflammation markers in patients with cystic fibrosis

Dayana Joyce Marques Queiroz , Alexandre Sérgio Silva , Celso Costa da Silva Júnior , Darlene Camati Persuhn , Alcides da Silva Diniz , Rafaela Lira Formiga Cavalcanti de Lima , Maria Paula de Paiva , Constantino Giovanni Braga Cartaxo , Patricia Gomes de Matos Bezerra , Mateus Duarte Ribeiro , Maria da Conceição Rodrigues Gonçalves

Publicado: 2022-05-23 / http://dx.doi.org/10.20960/nh.04253
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Trabajo Original: Evaluación del efecto in vitro de extractos intra y extracelulares de Lactobacillus contra la genotoxicidad y el estrés oxidativo causado por la acrilamida

Maria Goretti Reyes López , Adriana Cavazos Garduño , Nancy Elizabeth Franco Rodríguez , Jorge Manuel Silva Jara , Julio César Serrano Niño

Publicado: 2022-05-15 / http://dx.doi.org/10.20960/nh.04241
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Trabajo Original: Efecto de un multivitamínico sobre la resistencia a la insulina, inflamación y estrés oxidante en un modelo de obesidad inducida en ratas Wistar

José Antonio Palma-Jacinto , Isela Santiago-Roque , María del Rocío Coutiño-Rodríguez , Omar Elind Arroyo-Helguera

Publicado: 2023-01-31 / http://dx.doi.org/10.20960/nh.04621
Resumen | PDF

Trabajo Original: Capacidad de atrapamiento de radicales libres de la comida tradicional mexicana

María Teresa Sumaya-Martínez , Edgar Iván Jiménez-Ruiz , Marcela Robles-Machuca , Cristian Guillermo Valencia-Jurado , María Merced Romero-Chávez

Publicado: 2024-11-11 / http://dx.doi.org/10.20960/nh.05613
Resumen | PDF

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