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Iodine levels are associated with oxidative stress and antioxidant status in pregnant women with hypertensive disease

Sergio Cuellar-rufino, Mónica Navarro-meza, Pablo García-solís, Irene Xochihua-rosas, Omar Arroyo-helguera

VOLUMEN 34, NÚM. 3, mayo-junio (2017), PAG. 661-666

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Background: The antioxidant function of iodine and iodine deficiency as a risk factor of preeclampsia have been previously reported.Aim: To analyze the association between iodine deficiency, oxidative stress and antioxidant status with hypertensive disease of pregnancy (HPD).Method: Fifty-seven pregnant women were recruited in the last trimester of pregnancy; 20 were diagnosed with hypertensive disease (HPD) of pregnancy and 37 were normotensive pregnant women. Urinary iodine concentration (UIC), TSH, free T4 (fT4), total antioxidant status (FRP), superoxide dismutase (SOD), catalase (CAT), and oxidative stress (TBARS) were evaluated by colorimetric methods. Results: UIC median for all pregnant women was 151.9 µg/l. The UIC for pregnant women with HPD was 50-149 µg/l, compared to 150-249 µg/l in normotensive women. No significant differences in levels of TSH and fT4 in normotensive pregnant compared with HPD women were found. Pregnant women with HPD had significant high levels of TBARS, and significant low levels of FRP, SOD, CAT and UIC compared to normotensive pregnant. In addition, pregnant women with optimal levels of UIC had a higher SOD activity (r = 0.354, p = 0.011), while iodine deficiency was associated with HPD (r = -0,281, p = 0.039). Similarly, pregnant women with HPD had a significant negative association with SOD activity (r = -0.702, p = 0.005), CAT (r = -0.409, p = 0.002), and FRP (r = -0.624, p = 0.003), and a positive association with TBARS (r = 0.744, p = 0.001).Conclusion: Iodine contributes to redox balance during pregnancy; its deficiency is associated with HPD. This study shows the importance of iodine during pregnancy.

Palabras Clave: Iodine deficiency. Pregnancy-induced hypertension. Oxidative stress. Antioxidant status.



(2021) Excess iodine exposure. Asian Pacific Journal of Reproduction
Jin, Mingyue, Zhang, Zhuo, Li, Yongze, Teng, Di, Shi, Xiaoguang, Ba, Jianming, Chen, Bing, Du, Jianling, He, Lanjie, Lai, Xiaoyang, Teng, Xiaochun, Li, Yanbo, Chi, Haiyi, Liao, Eryuan, Liu, Chao, Liu, Libin, Qin, Guijun, Qin, Yingfen, Quan, Huibiao, Shi, Bingyin, Sun, Hui, Tang, Xulei, Tong, Nanwei, Wang, Guixia, Zhang, Jin-an, Wang, Youmin, Xue, Yuanming, Yan, Li, Yang, Jing, Yang, Lihui, Yao, Yongli, Ye, Zhen, Zhang, Qiao, Zhang, Lihui, Zhu, Jun, Zhu, Mei, Ning, Guang, Mu, Yiming, Zhao, Jiajun, Teng, Weiping, Shan, Zhongyan (2020) U-Shaped Associations Between Urinary Iodine Concentration and the Prevalence of Metabolic Disorders: A Cross-Sectional Study. Thyroid
Wang, Dandan, Wan, Siyuan, Liu, Peng, Meng, Fangang, Zhang, Xiaoye, Ren, Bingxuan, Qu, Mengying, Wu, Huaiyong, Shen, Hongmei, Liu, Lixiang (2021) Relationship between excess iodine, thyroid function, blood pressure, and blood glucose level in adults, pregnant women, and lactating women: A cross-sectional study. Ecotoxicology and Environmental Safety
Li, Jiang, Li, Jie, Sun, Ying, Fu, Yanqi, Shen, Wenqi, Cai, Lingli, Xu, Fei, Gao, Ling, Wang, Ningjian, Wang, Bin, Lu, Yingli (2025) Association of iodized salt intake with the risk of physical frailty in patients with type 2 diabetes. The Journal of nutrition, health and aging
Botchway, Benson O. A., Liu, Xuehong, Zhou, Yu, Fang, Marong (2023) Biometals in Alzheimer disease: emerging therapeutic and diagnostic potential of molybdenum and iodine. Journal of Translational Medicine
Businge, Charles Bitamazire, Longo-Mbenza, Benjamin, Kengne, Andre Pascal (2022) Iodine deficiency in pregnancy along a concentration gradient is associated with increased severity of preeclampsia in rural Eastern Cape, South Africa. BMC Pregnancy and Childbirth
Gajewska, Katarzyna, Laskowska, Marzena, Blazewicz, Anna (2021) Urinary iodine as an important indicator for preeclampsia: a Polish perspective. Current Issues in Pharmacy and Medical Sciences
Rodríguez-Cano, Ameyalli M, Calzada-Mendoza, Claudia C, Estrada-Gutierrez, Guadalupe, Mendoza-Ortega, Jonatan A, Perichart-Perera, Otilia (2020) Nutrients, Mitochondrial Function, and Perinatal Health. Nutrients
Habibi, Nahal, Jankovic-Karasoulos, Tanja, Leemaqz, Shalem Yiner-Lee, Francois, Maxime, Zhou, Shao Jia, Leifert, Wayne R., Perkins, Anthony V., Roberts, Claire T., Bianco-Miotto, Tina (2021) Effect of Iodine and Selenium on Proliferation, Viability, and Oxidative Stress in HTR-8/SVneo Placental Cells. Biological Trace Element Research
Zhang, Le, Shang, Fangjian, Liu, Cong, Zhai, Xiaodan (2024) The correlation between iodine and metabolism: a review. Frontiers in Nutrition
Liu, Zhao-Min, Wu, Yi, Long, Huan-Huan, Chen, Chao-Gang, Wang, Cheng, Ye, Yan-Bin, Shen, Zhen-Yu, Ye, Ming-Tong, Zhang, Su-Juan, Li, Min-Min, Pan, Wen-Jing (2023) Associations of Maternal Serum Iodine Concentration with Obstetric Complications and Birth Outcomes—Longitudinal Analysis Based on the Huizhou Mother–Infant Cohort, South China. Nutrients
Petca, Aida, Dimcea, Daiana Anne-Marie, Dumitrașcu, Mihai Cristian, Șandru, Florica, Mehedințu, Claudia, Petca, Răzvan-Cosmin (2023) Management of Hyperthyroidism during Pregnancy: A Systematic Literature Review. Journal of Clinical Medicine
Song, Eyun, Park, Min Jeong, Kim, Jung A, Roh, Eun, Yu, Ji Hee, Kim, Nam Hoon, Yoo, Hye Jin, Seo, Ji A, Kim, Sin Gon, Kim, Nan Hee, Baik, Sei Hyun, Choi, Kyung Mook (2022) Impact of urinary iodine concentration on blood glucose levels and blood pressure: a nationwide population-based study. European Journal of Nutrition
Priliani, Lidwina, Prado, Elizabeth L, Restuadi, Restuadi, Waturangi, Diana E, Shankar, Anuraj H, Malik, Safarina G (2019) Maternal Multiple Micronutrient Supplementation Stabilizes Mitochondrial DNA Copy Number in Pregnant Women in Lombok, Indonesia. The Journal of Nutrition
Reische, Elijah C., Männistö, Tuija, Purdue-Smithe, Alexandra, Kannan, Kurunthachalam, Kim, Un-Jung, Suvanto, Eila, Surcel, Heljä-Marja, Gissler, Mika, Mills, James L. (2021) The Joint Role of Iodine Status and Thyroid Function on Risk for Preeclampsia in Finnish Women: a Population-Based Nested Case-Control Study. Biological Trace Element Research
Candido, Aline Carare, Azevedo, Francilene Maria, Machamba, Almeida Abudo Leite, Pinto, Carina Aparecida, Lopes, Sílvia Oliveira, Macedo, Mariana de Souza, Ribeiro, Sarah Aparecida Vieira, Priore, Silvia Eloiza, Franceschini, Sylvia do Carmo Castro (2020) Implications of iodine deficiency by gestational trimester: a systematic review. Archives of Endocrinology and Metabolism
Businge, Charles Bitamazire, Usenbo, Anthony, Longo-Mbenza, Benjamin, Kengne, AP (2021) Insufficient iodine nutrition status and the risk of pre-eclampsia: a systemic review and meta-analysis. BMJ Open
Habibi, Nahal, Labrinidis, Agatha, Leemaqz, Shalem Yiner-Lee, Jankovic-Karasoulos, Tanja, McCullough, Dylan, Grieger, Jessica A., Gilbert, Sarah, Ricciardelli, Carmela, Zhou, Shao Jia, Perkins, Anthony V., Roberts, Claire T., Bianco-Miotto, Tina (2021) Effect of Selenium and Iodine on Oxidative Stress in the First Trimester Human Placenta Explants. Nutrients
Zhao, Jing, Su, Yinbiao, Zhang, Jin-An, Fang, Ming, Liu, Xuerong, Jia, Xi, Li, Xinming (2021) Inverse Association Between Iodine Status and Prevalence of Metabolic Syndrome: A Cross-Sectional Population-Based Study in a Chinese Moderate Iodine Intake Area. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Lokeswara, Angga Wiratama, Hiksas, Rabbania, Irwinda, Rima, Wibowo, Noroyono (2021) Preeclampsia: From Cellular Wellness to Inappropriate Cell Death, and the Roles of Nutrition. Frontiers in Cell and Developmental Biology
Habibi, Nahal, Grieger, Jessica A., Bianco-Miotto, Tina (2020) A Review of the Potential Interaction of Selenium and Iodine on Placental and Child Health. Nutrients
Businge, Charles Bitamazire, Longo-Mbenza, Benjamin, Kengne, Andre Pascal (2025) Circulating Potassium/Magnesium Ratio, Thyroid Stimulating Hormone, Fasting Plasma Glucose, Oxidized LDL/Albumin Ratio, and Urinary Iodine Concentration Are Possible Entities for Screening for Preeclampsia in Low-Resource Settings. Medicina
Businge, Charles Bitamazire, Madini, Namhla, Longo-Mbenza, Benjamin, Kengne, A P (2019) Insufficient iodine nutrition status and the risk of pre-eclampsia: a protocol for systematic review and meta-analysis. BMJ Open
Romero-Arauz JF, Morales-Borrego E, Garcia-Espinosa M, Peralta-Pedrero ML. [Clinical guideline. Preeclampsia-eclampsia]. Revista medica del Instituto Mexicano del Seguro Social 2012;50:569-79.
Van Dijk MG, Garcia-Rojas M, Contreras X, Krumholz A, Garcia SG, Diaz-Olavarrieta C. Treating patients with severe preeclampsia and eclampsia in Oaxaca, Mexico. Salud publica de Mexico 2014;56:426-7.
Pluta R, Ulamek-Koziol M, Furmaga-Jablonska W, Czuczwar SJ. Preeclampsia in the 21st century: Unresolved questions concerning etiology. Nutrition 2015;31:1179-81.
DOI: 10.1016/j.nut.2015.04.016
Many A, Hubel CA, Fisher SJ, Roberts JM, Zhou Y. Invasive cytotrophoblasts manifest evidence of oxidative stress in preeclampsia. The American journal of pathology 2000;156:321-31.
DOI: 10.1016/S0002-9440(10)64733-5
Vidal ZE, Rufino SC, Tlaxcalteco EH, et al. Oxidative stress increased in pregnant women with iodine deficiency. Biological trace element research 2014;157:211-7.
DOI: 10.1007/s12011-014-9898-6
Perez-Sepulveda A, Torres MJ, Khoury M, Illanes SE. Innate immune system and preeclampsia. Frontiers in immunology 2014;5:244.
DOI: 10.3389/fimmu.2014.00244
Laresgoiti-Servitje E. A leading role for the immune system in the pathophysiology of preeclampsia. Journal of leukocyte biology 2013;94:247-57.
DOI: 10.1189/jlb.1112603
Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK. Preeclampsia: an endothelial cell disorder. American journal of obstetrics and gynecology 1989;161:1200-4.
DOI: 10.1016/0002-9378(89)90665-0
Huang QT, Chen JH, Hang LL, Liu SS, Zhong M. Activation of PAR-1/NADPH oxidase/ROS signaling pathways is crucial for the thrombin-induced sFlt-1 production in extravillous trophoblasts: possible involvement in the pathogenesis of preeclampsia. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35:1654-62.
DOI: 10.1159/000373979
Huang QT, Zhang M, Zhong M, et al. Advanced glycation end products as an upstream molecule triggers ROS-induced sFlt-1 production in extravillous trophoblasts: a novel bridge between oxidative stress and preeclampsia. Placenta 2013;34:1177-82.
DOI: 10.1016/j.placenta.2013.09.017
Palan PR, Mikhail MS, Romney SL. Placental and serum levels of carotenoids in preeclampsia. Obstetrics and gynecology 2001;98:459-62.
Elind A-HO. Trace Elements as Potential Biomarkers of Preeclampsia. Annual Research & Review in Biology 2015;9:1-10.
Glinoer D. The importance of iodine nutrition during pregnancy. Public health nutrition 2007;10:1542-6.
DOI: 10.1017/S1368980007360886
Glinoer D. The regulation of thyroid function during normal pregnancy: importance of the iodine nutrition status. Best practice & research Clinical endocrinology & metabolism 2004;18:133-52.
DOI: 10.1016/j.beem.2004.03.001
Gulaboglu M, Borekci B, Delibas I. Urine iodine levels in preeclamptic and normal pregnant women. Biological trace element research 2010;136:249-57.
DOI: 10.1007/s12011-009-8539-y
Borekci B, Gulaboglu M, Gul M. Iodine and magnesium levels in maternal and umbilical cord blood of preeclamptic and normal pregnant women. Biological trace element research 2009;129:1-8.
DOI: 10.1007/s12011-008-8278-5
Gulaboglu M, Borekci B, Halici Z. Placental tissue iodine level and blood magnesium concentration in pre-eclamptic and normal pregnancy. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2007;98:100-4.
DOI: 10.1016/j.ijgo.2007.03.047
Thomas EL, Aune TM. Cofactor role of iodide in peroxidase antimicrobial action against Escherichia coli. Antimicrobial agents and chemotherapy 1978;13:1000-5.
DOI: 10.1128/AAC.13.6.1000
Shrivastava A, Tiwari M, Sinha RA, et al. Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway. The Journal of biological chemistry 2006;281:19762-71.
DOI: 10.1074/jbc.M600746200
Arroyo-Helguera O, Rojas E, Delgado G, Aceves C. Signaling pathways involved in the antiproliferative effect of molecular iodine in normal and tumoral breast cells: evidence that 6-iodolactone mediates apoptotic effects. Endocrine-related cancer 2008;15:1003-11.
DOI: 10.1677/ERC-08-0125
Arroyo-Helguera O, Anguiano B, Delgado G, Aceves C. Uptake and antiproliferative effect of molecular iodine in the MCF-7 breast cancer cell line. Endocrine-related cancer 2006;13:1147-58.
DOI: 10.1677/erc.1.01250
Olivo-Vidal ZE, Rodriguez RC, Arroyo-Helguera O. Iodine Affects Differentiation and Migration Process in Trophoblastic Cells. Biological trace element research 2016;169:180-8.
DOI: 10.1007/s12011-015-0433-1
Venturi S, Venturi M. Iodide, thyroid and stomach carcinogenesis: evolutionary story of a primitive antioxidant? European journal of endocrinology / European Federation of Endocrine Societies 1999;140:371-2.
Nunez-Anita RE, Arroyo-Helguera O, Cajero-Juarez M, Lopez-Bojorquez L, Aceves C. A complex between 6-iodolactone and the peroxisome proliferator-activated receptor type gamma may mediate the antineoplastic effect of iodine in mammary cancer. Prostaglandins & other lipid mediators 2009;89:34-42.
DOI: 10.1016/j.prostaglandins.2009.04.001
Yoo HY, Chang MS, Rho HM. Induction of the rat Cu/Zn superoxide dismutase gene through the peroxisome proliferator-responsive element by arachidonic acid. Gene 1999;234:87-91.
DOI: 10.1016/S0378-1119(99)00176-6
Smyth PP. Role of iodine in antioxidant defence in thyroid and breast disease. BioFactors 2003;19:121-30.
DOI: 10.1002/biof.5520190304
Sinha AK. Colorimetric assay of catalase. Analytical biochemistry 1972;47:389-94.
DOI: 10.1016/0003-2697(72)90132-7
Madesh M, Balasubramanian KA. Microtiter plate assay for superoxide dismutase using MTT reduction by superoxide. Indian journal of biochemistry & biophysics 1998;35:184-8.
Cable RG. Hemoglobin determination in blood donors. Transfusion medicine reviews 1995;9:131-44.
DOI: 10.1016/S0887-7963(05)80052-5
Mendez-Villa L, Elton-Puente JE, Solis SJ, et al. Iodine nutrition and thyroid function assessment in childbearing age women from Queretaro, Mexico. Nutricion hospitalaria 2014;29:204-11.
Garcia-Solis P, Solis SJ, Garcia-Gaytan AC, et al. Iodine nutrition in elementary state schools of Queretaro, Mexico: correlations between urinary iodine concentration with global nutrition status and social gap index. Arquivos brasileiros de endocrinologia e metabologia 2013;57:473-82.
DOI: 10.1590/S0004-27302013000600010
Homero Martínez-Salgado RC-L, Diana Lechuga-Martín del Campo, Rosa Isela Ramos-Hernández, Maribel Orozco-López, Juan Rivera-Dommarco,, Iván Mendoza CM. Deficiencia de yodo y otros posibles bociógenos en la persistencia del bocio endémico en México. Gaceta Médica Mexico 2002;138.
Hecht F, Pessoa CF, Gentile LB, Rosenthal D, Carvalho DP, Fortunato RS. The role of oxidative stress on breast cancer development and therapy. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016.
Elliot MG. Oxidative stress and the evolutionary origins of preeclampsia. Journal of reproductive immunology 2016;114:75-80.
DOI: 10.1016/j.jri.2016.02.003
Tousoulis D, Psaltopoulou T, Androulakis E, et al. Oxidative stress and early atherosclerosis: novel antioxidant treatment. Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2015;29:75-88.
DOI: 10.1007/s10557-014-6562-5
Sanchez-Aranguren LC, Prada CE, Riano-Medina CE, Lopez M. Endothelial dysfunction and preeclampsia: role of oxidative stress. Frontiers in physiology 2014;5:372.
DOI: 10.3389/fphys.2014.00372
Can M, Guven B, Bektas S, Arikan I. Oxidative stress and apoptosis in preeclampsia. Tissue & cell 2014;46:477-81.
DOI: 10.1016/j.tice.2014.08.004
Sharma JB, Sharma A, Bahadur A, Vimala N, Satyam A, Mittal S. Oxidative stress markers and antioxidant levels in normal pregnancy and pre-eclampsia. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2006;94:23-7.
DOI: 10.1016/j.ijgo.2006.03.025
Karacay O, Sepici-Dincel A, Karcaaltincaba D, et al. A quantitative evaluation of total antioxidant status and oxidative stress markers in preeclampsia and gestational diabetic patients in 24-36 weeks of gestation. Diabetes research and clinical practice 2010;89:231-8.
DOI: 10.1016/j.diabres.2010.04.015
Braekke K, Harsem NK, Staff AC. Oxidative stress and antioxidant status in fetal circulation in preeclampsia. Pediatric research 2006;60:560-4.
DOI: 10.1203/01.pdr.0000242299.01219.6a
Llurba E, Gratacos E, Martin-Gallan P, Cabero L, Dominguez C. A comprehensive study of oxidative stress and antioxidant status in preeclampsia and normal pregnancy. Free radical biology & medicine 2004;37:557-70.
DOI: 10.1016/j.freeradbiomed.2004.04.035
Wu YX, Li LJ, Chen GY, Zhao WD, Qiu MC. [Effects of supplementation of different kinds of iodine on the antioxidative ability of retina in iodine deficient rats]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 2003;39:495-8.
Moser M, Buchberger W, Mayer H, Winkler R. [Influence of an iodine-drinking cure on the antioxidative status of diabetic patients]. Wiener klinische Wochenschrift 1991;103:183-6.

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Trabajo Original: Mineral and/or milk supplementation of fruit beverages helps in the prevention of H2O2-induced oxidative stress in Caco-2 cells

Publicado: 2021-06-25 / http://dx.doi.org/
Resumen | PDF

Trabajo Original: Dietary intake and oxidative stress in breast cancer: before and after treatments

Publicado: 2021-06-28 / http://dx.doi.org/
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Trabajo Original: Efecto de la suplementación con antioxidantes sobre el estrés oxidativo y la calidad de vida durante el tratamiento oncológico en pacientes con cáncer cérvico uterino

Publicado: 2021-06-28 / http://dx.doi.org/
Resumen | PDF

Revisión: Meta-análisis del papel del licopeno en la diabetes mellitus tipo 2

Publicado: 2021-07-02 / http://dx.doi.org/
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Trabajo Original: Problemática nutricional en fumadores y fumadores pasivos

Rosa M. Ortega , Ana Isabel Jiménez-Ortega , Rosa María Martínez García , Ana María Lorenzo-Mora , María del Carmen Lozano-Estevan

Publicado: 2021-07-20 / http://dx.doi.org/10.20960/nh.03794
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Revisión: The role of hyperglycemia in the induction of oxidative stress and inflammatory process

Publicado: 2021-10-04 / http://dx.doi.org/
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Trabajo Original: Enzyme activity of superoxide dismutase and zincemia in women with preeclampsia

Publicado: 2021-10-19 / http://dx.doi.org/
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Trabajo Original: Estrés oxidativo; estudio comparativo entre un grupo de población normal y un grupo de población obesa mórbida

Publicado: 2021-10-25 / http://dx.doi.org/
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Trabajo Original: Relación del estrés oxidativo y la pérdida de peso obtenida en pacientes obesos mórbidos mediante cirugía bariátrica con la técnica del cruce duodenal

Publicado: 2021-10-26 / http://dx.doi.org/
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Trabajo Original: Peroxidación de lípidos y la respuesta del sistema de defensa antioxidante en el diabético tipo 2 obeso en comparación al diabético tipo 2 sin obesidad

Publicado: 2021-10-28 / http://dx.doi.org/
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Trabajo Original: Prevalence of metilentetrahidrofolate reductase C677T polymorphism, consumption of vitamins B6, B9, B12 and determination of lipidic hydroperoxides in obese and normal weight Mexican population

Publicado: 2021-10-29 / http://dx.doi.org/
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Revisión: Micronutrients influencing the immune response in leprosy

Publicado: 2021-11-02 / http://dx.doi.org/
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Trabajo Original: Interaction between mercury (Hg), arsenic (As) and selenium (Se) affects the activity of glutathione S-transferase in breast milk; possible relationship with fish and shellfish intake

Publicado: 2021-11-04 / http://dx.doi.org/
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Trabajo Original: Defensas antioxidantes en leche materna en relación al número de gestas y a la edad de las madres

Publicado: 2021-11-08 / http://dx.doi.org/
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Trabajo Original: Influence of magnesium on biochemical parameters of iron and oxidative stress in patients with type 2 diabetes

Publicado: 2021-11-08 / http://dx.doi.org/
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Trabajo Original: Hypoalbuminemia and oxidative stress in patients on renal hemodialysis program

Publicado: 2021-11-15 / http://dx.doi.org/
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Trabajo Original: Indicadores de estrés oxidativo en suero y comportamiento alimentario en adultos de una zona rural de Jalisco, México

Publicado: 2021-11-18 / http://dx.doi.org/
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Trabajo Original: High-protein diet induces oxidative stress in rat brain: protective action of high-intensity exercise against lipid peroxidation

Publicado: 2021-11-25 / http://dx.doi.org/
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Trabajo Original: Glycemic Control and Oxidative Stress Markers and their relationship with the Thioredoxin Interacting Protein (TXNIP) gene in Type 2 Diabetic patients

Publicado: 2021-11-25 / http://dx.doi.org/
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Trabajo Original: Effect of computer radiation on weight and oxidant-antioxidant status of mice

Publicado: 2021-11-25 / http://dx.doi.org/
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Trabajo Original: Factores que inciden el daño oxidativo en niños con obesidad: estudio piloto

Publicado: 2021-11-26 / http://dx.doi.org/
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Trabajo Original: Purine nucleoside phosphorylase and the enzymatic antioxidant defense system in breast milk from women with different levels of arsenic exposure

Publicado: 2021-11-30 / http://dx.doi.org/
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Trabajo Original: Reduction of serum advanced glycation end-products with a low calorie Mediterranean diet

Publicado: 2021-11-30 / http://dx.doi.org/
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Trabajo Original: Fish oil and vitamin E change lipid profiles and anti-LDL-antibodies in two different ethnic groups of women transitioning through menopause

Publicado: 2021-12-01 / http://dx.doi.org/
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Trabajo Original: Effect of long term intake of white tea on acute oxidative stress in rats

Publicado: 2022-01-11 / http://dx.doi.org/
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Trabajo Original: Relationship between zincemia, superoxide dismutase activity and marker of oxidative stress in women with breast cancer

Publicado: 2022-01-12 / http://dx.doi.org/
Resumen | PDF

Revisión: Potencial antioxidante de la miel de Melipona beecheii y su relación con la salud: una revisión

Publicado: 2022-01-19 / http://dx.doi.org/
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Trabajo Original: Glutathione peroxidase-1 Pro200Leu polymorphism (rs1050450) is associated with morbid obesity independently of the presence of prediabetes or diabetes in women from Central Mexico

Publicado: 2022-01-19 / http://dx.doi.org/
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Trabajo Original: Dietary fish oil increases catalase activity in patients with probable Alzheimer’s disease

Blanca M. G. Torres-Mendoza , Genaro Gabriel Ortiz , Lorenzo Sánchez-Romero , Daniela L. C. Delgado-Lara , María T. García Martínez , Mario-Alberto Mireles-Ramírez , José Antonio Cruz Serrano , Fermín Paul Pacheco Moisés

Publicado: 2022-04-08 / http://dx.doi.org/10.20960/nh.04153
Resumen | PDF

Trabajo Original: Vitamin D levels and their association with oxidative stress and inflammation markers in patients with cystic fibrosis

Dayana Joyce Marques Queiroz , Alexandre Sérgio Silva , Celso Costa da Silva Júnior , Darlene Camati Persuhn , Alcides da Silva Diniz , Rafaela Lira Formiga Cavalcanti de Lima , Maria Paula de Paiva , Constantino Giovanni Braga Cartaxo , Patricia Gomes de Matos Bezerra , Mateus Duarte Ribeiro , Maria da Conceição Rodrigues Gonçalves

Publicado: 2022-05-23 / http://dx.doi.org/10.20960/nh.04253
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Trabajo Original: Evaluación del efecto in vitro de extractos intra y extracelulares de Lactobacillus contra la genotoxicidad y el estrés oxidativo causado por la acrilamida

Maria Goretti Reyes López , Adriana Cavazos Garduño , Nancy Elizabeth Franco Rodríguez , Jorge Manuel Silva Jara , Julio César Serrano Niño

Publicado: 2022-05-15 / http://dx.doi.org/10.20960/nh.04241
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Trabajo Original: Efecto de un multivitamínico sobre la resistencia a la insulina, inflamación y estrés oxidante en un modelo de obesidad inducida en ratas Wistar

José Antonio Palma-Jacinto , Isela Santiago-Roque , María del Rocío Coutiño-Rodríguez , Omar Elind Arroyo-Helguera

Publicado: 2023-01-31 / http://dx.doi.org/10.20960/nh.04621
Resumen | PDF

Trabajo Original: Capacidad de atrapamiento de radicales libres de la comida tradicional mexicana

María Teresa Sumaya-Martínez , Edgar Iván Jiménez-Ruiz , Marcela Robles-Machuca , Cristian Guillermo Valencia-Jurado , María Merced Romero-Chávez

Publicado: 2024-11-11 / http://dx.doi.org/10.20960/nh.05613
Resumen | PDF

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