Nutrición Hospitalaria 05284 / http://dx.doi.org/10.20960/nh.05284

Resumen| PDF (ENGLISH)

Trabajo Original

Do nutritional assessment scores have a relationship with transthyretin levels?

Marcela Almeida Linden, Renata Germano Borges de Oliveira Nascimento Freitas, Lidiane Oliveira de Souza Teles, André Moreno Morcillo, Matthew Thomas Ferreira, Roberto Jose Negrão Nogueira

Prepublicado: 2024-10-30

Publicado: 2024-12-16

VOLUMEN 41, NÚM. 6, noviembre-diciembre (2024), PAG. 1246-1252

Logo Descargas Número de descargas: 4006 Logo Visitas Número de visitas: 921 Citas Citas: 0

Compártelo:

Background and aims: nutritional screening tools assess factors like weight loss, BMI, food intake, and disease severity to determine a patient's nutritional risk and needed care. Plasma transthyretin is a practical measurement used to assess nutritional evolution due to its rapid response to food intake. This study examines the relationship between nutritional scores, transthyretin protein levels, and the possibility of death. Methods: the sample consisted of 302 patients hospitalized in the wards or intensive care unit of a public teaching hospital, using parenteral nutrition as the primary source of nutrition. Five nutritional screening tools were applied, and patient charts were verified for transthyretin levels. Results: from the sample, 260 were adults, and 42 were children, with a mean age of 48.3 years. When evaluating the patient's outcome in relation to the scores, the Malnutrition Universal Screening Tool proved to be better at predicting death (p-value = 0.02). None of the scores were related to transthyretin levels, showing that lower transthyretin values did not influence nutritional risk. Conclusion: we believe early identification of nutritional risk through nutritional scores is necessary for better nutritional monitoring to minimize unfavorable outcomes. This study corroborates the more recent concept that transthyretin is not useful for determining unfavorable outcomes in hospitalized patients with a severe inflammatory process. In clinical practice, identifying a patient at nutritional risk according to the Malnutrition Universal Screening Tool and promoting adequate nutritional monitoring may reduce mortality.

Palabras Clave: Transthyretin. Nutrition assessment. Nutritional scores.

Descargar PDF (ENGLISH)

Bibliografía
Artículos Relacionados

Please find attached the file containing the manuscript “Do nutritional assessment scores have a relationship with transthyretin levels?” by Linden et al. As corresponding author, I am submitting this on behalf of all coauthors for possible publication as an Original Article in Nutrición Hospitalaria. The data is original, was not submitted to another journal, and all authors agreed with its content and have contributed to the work. No conflicts of interest are declared for any of the authors.

It is known that early identification of the patient at nutritional risk is fundamental in the elaboration of a follow-up plan. This article showed a positive association between the Malnutrition Universal Screening Tool, nutritional assessment score, and mortality in this population, thus identifying patients at higher nutritional risk and treating them appropriately, in addition to promoting recovery of nutritional status, it can also reduce mortality in patients using parenteral nutrition.

Thank you for your consideration of this manuscript and we are looking forward to hearing from you.

Sincerely,

Dent E, Hoogendijk EO, Visvanathan R, Wright ORL. Malnutrition Screening and Assessment in Hospitalised Older People: A Review. J Nutr Heal Aging. 2019;23:431-441.
DOI: 10.1007/s12603-019-1176-z

Cederholm T, Bosaeus I, Barazzoni R, et al. Diagnostic criteria for malnutrition - An ESPEN Consensus Statement. Clin Nutr. 2015;34:335-340.
DOI: 10.1016/j.clnu.2015.03.001

Stratton RJ, Hackston A, Longmore D, et al. Malnutrition in hospital outpatients and inpatients: prevalence, concurrent validity and ease of use of the ‘malnutrition universal screening tool’ (‘MUST’) for adults. Br J Nutr. 2004;92:799.
DOI: 10.1079/BJN20041258

Guigoz Y, Vellas B, Garry PJ. Nutrition Surveys in the Elderly. Nutrition. 1996;54(January):S59-S65. papers3://publication/uuid/DEB3C60E-114D-4B03-A37B-34F745656610

Kondrup J, Ramussen HH, Hamberg O, et al. Nutritional risk screening (NRS 2002): A new method based on an analysis of controlled clinical trials. Clin Nutr. 2003;22:321-336.
DOI: 10.1016/S0261-5614(02)00214-5

Rosa M, Heyland DK, Fernandes D, Rabito EI, Oliveira ML, Marcadenti A. Translation and adaptation of the NUTRIC Score to identify critically ill patients who benefit the most from nutrition therapy. Clin Nutr ESPEN. 2016;14:31-36.
DOI: 10.1016/j.clnesp.2016.04.030

Hulst JM, Zwart H, Hop WC, Joosten KFM. Dutch national survey to test the STRONGkids nutritional risk screening tool in hospitalized children. Clin Nutr. 2010;29:106-111.
DOI: 10.1016/j.clnu.2009.07.006

Dellière S, Cynober L. Is transthyretin a good marker of nutritional status? Clin Nutr. 2017;36:364-370.
DOI: 10.1016/j.clnu.2016.06.004

World Health Organization. Obesity: preventing and managing the global epidemic. Report of a World Health Organization Consultation. Geneva World Heal Organ. 2000;WHO Obesit 284:256.

Chumlea WC, Guo SS, Steinbaugh ML. Prediction of stature from knee height for black and White adults and children with application to mobility impaired or handicapped persons. J Am Diet Assoc. 1994;94:1385-1388.
DOI: 10.1016/0002-8223(94)92540-2

Onis M de, Onyango A, Borghi E, Siyam A, Pinol A. The new WHO child growth standards. Paediatr Croat Suppl. 2008;52:13-17.

Organização Pan-Americana (OPAS). XXXVI Reunión del Comitê Asesor de Ivestigaciones en Salud – Encuestra Multicêntrica – Salud Beinestar y Envejecimeiento (SABE) en América Latina e el Caribe – Informe preliminar. Screening. Published online 2002:22.

Carvalho FC de, Lopes CR, Vilela LC, Vieira MA, Rinaldi AEM, Crispim CA. Tradução e adaptação cultural da ferramenta Strongkids para triagem do risco de desnutrição em crianças hospitalizadas Translation and cross-cultural adaptation of the Strongkids tool for screening of malnutrition risk in hospitalized children. Rev Paul Pediatr. 2013;31:159-165.
DOI: 10.1590/S0103-05822013000200005

Clínicas HDE, Unicamp DA. Série Manuais do Manual de Processos de Trabalho da Universidade Estadual de Campinas. Published online 2011:1-156.

Evans DC, Corkins MR, Malone A, et al. The Use of Visceral Proteins as Nutrition Markers: An ASPEN Position Paper. Nutr Clin Pract. 2021;36:22-28.
DOI: 10.1002/ncp.10588

Vries de MC, Koekkoek W, Opdam MH, Van Blokland D, Van Zanten AR. Nutritional assessment of critically ill patients: Validation of the modified NUTRIC score. Eur J Clin Nutr. 2018;72:428-435.
DOI: 10.1038/s41430-017-0008-7

Vliet van IMY, Gomes-Neto AW, de Jong MFC, Bakker SJL, Jager-Wittenaar H, Navis GJ. Malnutrition screening on hospital admission: impact of overweight and obesity on comparative performance of MUST and PG-SGA SF. Eur J Clin Nutr. 2021;75:1398-1406.
DOI: 10.1038/s41430-020-00848-4

Rabito EI, Marcadenti A, Da Silva Fink J, Figueira L, Silva FM. Nutritional Risk Screening 2002, Short Nutritional Assessment Questionnaire, Malnutrition Screening Tool, and Malnutrition Universal Screening Tool Are Good Predictors of Nutrition Risk in an Emergency Service. Nutr Clin Pract. 2017;32:526-532.
DOI: 10.1177/0884533617692527

Gomes-Neto AW, van Vliet IMY, Osté MCJ, et al. Malnutrition Universal Screening Tool and Patient-Generated Subjective Global Assessment Short Form and their predictive validity in hospitalized patients. Clin Nutr ESPEN. 2021;45:252-261.
DOI: 10.1016/j.clnesp.2021.08.015

Liu G, Zhang S, Mao Z, Wang W, Hu H. Clinical significance of nutritional risk screening for older adult patients with COVID-19. Eur J Clin Nutr. 2020;74:876-883.
DOI: 10.1038/s41430-020-0659-7

Luca S, Niels H, Ballmer PE, Maya R, Reinhard I. Nrs-2002 components, nutritional score and severity of disease score, and their association with hospital length of stay and mortality. Swiss Med Wkly. 2021;151.
DOI: 10.4414/smw.2021.20517

Grolimund Berset D, Guex E, Valentinuzzi N, Borens O, Wild P, Coti Bertrand P. Improving nutritional care quality in the orthopedic ward of a Septic Surgery Center by implementing a preventive nutritional policy using the Nutritional Risk Score: a pilot study. Eur J Clin Nutr. 2019;73:276-283.
DOI: 10.1038/s41430-018-0345-1

Zhao X, Li Y, Ge Y, et al. Evaluation of Nutrition Risk and Its Association With Mortality Risk in Severely and Critically Ill COVID-19 Patients. J Parenter Enter Nutr. 2021;45:32-42.
DOI: 10.1002/jpen.1953

Akbar MR, Pranata R, Wibowo A, Lim MA, Sihite TA, Martha JW. The association between serum prealbumin and poor outcome in COVID-19 – Systematic review and meta-analysis. Eur Rev Med Pharmacol Sci. 2021;25:3879-3885.

Chada RR, Chidrawar S, Goud BA, Maska A, Medanki R, Nagalla B. Association Between Nutrition Delivery, Modified Nutrition Risk In Critically III Score, and 28-Day Mortality. Nutr Clin Pract. 2021;36:1020-1033.
DOI: 10.1002/ncp.10673

Shaaban S, Nassar M, El-Gendy Y, El-Shaer B. Nutritional risk screening of hospitalized children aged < 3 years. East Mediterr Heal J. 2019;25:18-23.
DOI: 10.26719/emhj.18.019

Artículos Relacionados:

Trabajo Original: Seguimiento a un año del estado nutricional de los pacientes sometidos a trasplante hepático

Maria Eugenia Deutrich Aydos , Sabrina Alves Fernandes , Flávia Feijó Nunes , Lílian Bassani , Lara Rigon Leonhardt , Daniele Lazzarotto Harter , Bianca Pivato , Daniella Miranda , Cláudio Augusto Marroni

Publicado: 2016-02-16 / http://dx.doi.org/10.20960/nh.8

Resumen | PDF

Trabajo Original: La circunferencia de la pantorrilla como marcador rápido y fiable de desnutrición en el anciano que ingresa en el hospital. relación con la edad y sexo del paciente

Emilia María López Lirola , María Concepción Iríbar Ibabe , José María Peinado Herreros

Publicado: 2016-06-30 / http://dx.doi.org/10.20960/nh.262

Resumen | PDF

Trabajo Original: Asociación de los indicadores antropométricos y de composición corporal en la predicción de la resistencia a la insulina en pacientes con enfermedad de las arterias coronarias

Larissa Pessoa Vila Nova , Cristiane Maria Araújo Tavares De Sá , Maria Cleide Freire Clementino Da Silva , Marinaldo Freire Lustosa , Rafael Augusto Batista De Medeiros , Daniel Calado Brito , Maria Goretti Pessoa de Araújo Burgos

Publicado: 2016-07-18 / http://dx.doi.org/10.20960/nh.376

Resumen | PDF

Trabajo Original: Relación entre índices antropométricos de salud con el consumo de alimentos en adultos mayores físicamente activos

Pablo Antonio Valdés-Badilla , Andres Godoy-cumillaf , Jenny Ortega-spuler , Daniela Díaz-aravena , Nibaldo Castro-garrido , Luis Sandoval-muñoz , Tomás Herrera-Valenzuela , Antonio López-Fuenzalida , Rodrigo Vargas-vitoria , Samuel Durán-agüero

Publicado: 2017-02-01 / http://dx.doi.org/10.20960/nh.1012

Resumen | PDF

Trabajo Original: Nutritional evaluation of geriatric patients with alzheimer’s disease in southern brazil: case-control study

Flávia Ivanski , Lizziane de Paula Nascimento , Bárbara Luisa Fermino , Juliana Sartori Bonini , Weber Cláudio Francisco Nunes da Silva , Juliana Maria Silva Valério , Roberta Fabbri , Anne Karine Bosetto , Elizama Gregório

Publicado: 2017-10-09 / http://dx.doi.org/10.20960/nh.1626

Resumen | PDF

Trabajo Original: Early application of Global Subjective Evaluation Produced by the Patient and survival in patients with cancer

Alexsandro Ferreira dos Santos , Alexsandro Ferreira dos Santos , Lyrian Lorena Freire Lira , Gabriela Nunes Braga , Maria Tereza Borges Frota , Rita Da Graça Carvalhal Frazão Correa , Maria Bethânia Da Costa Chein

Publicado: 2018-04-30 / http://dx.doi.org/10.20960/nh.2018

Resumen | PDF

Trabajo Original: Phase angle and mid arm circumference as predictors of protein energy wasting in renal replacement therapy patients

Gabriela Leal-Escobar , Iván Armando Osuna-Padilla , Karla Berenice Cano Escobar , Bernardo Moguel González , Héctor Alejandro Pérez Grovas , Silvia Ruiz Ubaldo

Publicado: 2018-12-12 / http://dx.doi.org/10.20960/nh.2463

Resumen | PDF

Trabajo Original: Nutritional diagnosis of patients with hepatocellular carcinoma: what is the best method?

Daniella Miranda da Silva , Ana Cristhina Henz , Sabrina Alves Fernandes , Cláudio Augusto Marroni

Publicado: 2019-02-10 / http://dx.doi.org/10.20960/nh.02542

Resumen | PDF

Trabajo Original: Nutrición y gastronomía en la comunidad autónoma de La Rioja. Evolución del modelo alimentario, de la identidad gastronómica y de la valoración nutricional de la dieta

Miren Quemada Jorcano

Publicado: 2019-05-17 / http://dx.doi.org/10.20960/nh.02692

Resumen | PDF

Trabajo Original: Nutritional assessment of female patients newly diagnosed with breast cancer in a northern region of Spain

Liliana Cabo García , María Purificación González González , Elena Alonso-Aperte , José Luis Rodicio Miravalles , David Rodríguez Rubí , María Achón Tuñón

Publicado: 2019-07-18 / http://dx.doi.org/10.20960/nh.02788

Resumen | PDF

Nota Clínica: Hipocupremia severa y polineuropatía amiloidótica familiar por transtiretina

María Teresa Fernández López , Cristina Guillín Amarelle , José Antonio Mato Mato

Publicado: 2019-07-02 / http://dx.doi.org/10.20960/nh.02771

Resumen | PDF

Trabajo Original: A comparison of the nutritional profile and price of gluten-free products and their gluten-containing counterparts available in the Spanish market

Nancy Babio , Núria Lladó Bellette , María Besora-Moreno , Gemma Castillejo , Núria Guillén , Francesc Martínez-Cerezo , Elisenda Vilchez , Esther Roger , Pablo Hernández-Alonso , Jordi Salas Salvadó

Publicado: 2020-01-25 / http://dx.doi.org/10.20960/nh.03016

Resumen | PDF

Trabajo Original: SARC-CalF-assessed risk of sarcopenia and associated factors in cancer patients

Vanusa Felício de Souza , Thamirys de Souza Chaves Ribeiro , Rayne de Almeida Marques , Glenda Blaser Petarli , Taísa Sabrina Silva Pereira , Jose Luiz Marques Rocha , Valdete Regina Guandalini

Publicado: 2020-05-14 / http://dx.doi.org/10.20960/nh.03158

Resumen | PDF

Trabajo Original: Sum of skinfolds measurement can be used in the estimation of total body fat in patients with chronic kidney disease undergoing hemodialysis

Dejane de Almeida Melo , Elane Viana Furtado Hortegal , Alana Caroline Amorim de Miranda Guimarães , Ana Karina Teixeira da Cunha França , Janete Janete Daniel Alencar Alves , Elisângela Milhomem dos Santos , Thanara da Conceição da Silva , Jacqueline Carvalho Galvão da Silva , Liliane Carvalho Rodrigues Nunes , Suena Cristina Rodrigues de Carvalho , Laís Ferreira de Sousa , Rafael Ferreira Nunes , Raimunda Sheyla Carneiro Dias , Alcione Miranda dos Santos

Publicado: 2020-09-15 / http://dx.doi.org/10.20960/nh.03338

Resumen | PDF

Trabajo Original: Nutritional guidance, monitoring, and supplementation before and after bariatric surgery — Are we doing this correctly?

Mariane Marques da Silva , Dan Linetzky Waitzberg , Regiane Macedo Silva Dipppolito , Priscila Sala , Samira Barcelos , Marco Aurélio Santo , Ana Cristina Martinez , Raquel Susana Torrinhas

Publicado: 2020-06-22 / http://dx.doi.org/10.20960/nh.03221

Resumen | PDF

Trabajo Original: Influencia de la historia de isquemia sobre el estado nutricional en pacientes ingresados por accidente cerebrovascular

Rebeca Jiménez Sahagún , Juan José López Gómez , Cristina Serrano Valles , Jennifer Fernández de los Muros Mato , Susana García Calvo , Beatriz Torres Torres , Emilia Gómez Hoyos , Daniel de Luis Román

Publicado: 2020-12-12 / http://dx.doi.org/10.20960/nh.03479

Resumen | PDF

Trabajo Original: Desnutrición relacionada con la enfermedad, parámetros funcionales y costes asociados en un hospital general

Pablo Barcina Pérez , María Teresa Mercader Ros , Oriol Abellán Aynes , José María Cayuela García , Juana Góngora Hervás , Pedro Hernández Jiménez , Carmen Lucas Abellán

Publicado: 2020-12-01 / http://dx.doi.org/10.20960/nh.03464

Resumen | PDF

Trabajo Original: Evaluación del estado nutricional al ingreso y evolución tras siete días de hospitalización en un hospital de segundo nivel de Madrid

Alberto Villaverde-Núñez , Cristina Pérez Ramos , María Victoria Sanz Lobo , María del Carmen Morgado Benito , Virginia Martínez-Ibáñez , Noelia Avecilla Nieto , Cristina Antón Rodríguez

Publicado: 2021-01-02 / http://dx.doi.org/10.20960/nh.03499

Resumen | PDF

Trabajo Original: Interleukin-6 and triceps skinfold are associated with severity/cancer stage in newly-diagnosed colorectal cancer patients

Samara Bomfim Gomes Campos , Amylly Sanuelly da Paz Martins , Anne Karolyne dos Santos , Marília Oliveira Fonseca Goulart , Fabiana Andréa Moura

Publicado: 2021-05-13 / http://dx.doi.org/10.20960/nh.03696

Resumen | PDF

Trabajo Original: Prevalencia y factores asociados a desnutrición entre pacientes ingresados en un hospital de media-larga estancia

Publicado: 2021-06-24 / http://dx.doi.org/

Resumen | PDF

Revisión: Burns, metabolism and nutritional requirements

Publicado: 2021-06-28 / http://dx.doi.org/

Resumen | PDF

Trabajo Original: Long-term nutritional assessment of patients with severe short bowel syndrome managed with home enteral nutrition and oral intake

Publicado: 2021-06-28 / http://dx.doi.org/

Resumen | PDF

Trabajo Original: Hip fracture prognosis: could bioimpedance be an alternative to conventional nutritional assessment?

Publicado: 2021-06-28 / http://dx.doi.org/

Resumen | PDF

Trabajo Original: Evaluation of the mini-nutritional assessment short-form (MNA-SF) among institutionalized older patients in Spain

Publicado: 2021-07-02 / http://dx.doi.org/

Resumen | PDF

Trabajo Original: Riesgo nutricional y desenlaces clínicos en pacientes con diagnóstico de COVID-19 en una red hospitalaria de alta complejidad

Olga Lucía Pinzón-Espitia , Juan Mauricio Pardo-Oviedo , Luisa Fernanda Murcia Soriano

Publicado: 2021-06-11 / http://dx.doi.org/10.20960/nh.03738

Resumen | PDF