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As the last century saw a decline in the burden of nutritional deficiency and infectious disease, the global burden of chronic disease, cardiovascular disease (CVD) in particular, is increasing. CVD is the leading cause of death in the developed countries. Significant research efforts on the prevention and treatment of this disease have identified elevated plasma cholesterol as a primary risk factor for CVD. Although CVD progresses with hypercholesterolemia, it seems possibility to delay and prevent its development through improvement of diet. Recent findings demonstrate that protein concentrates, protein hydrolysates, and peptides derived from vegetables may promote a significant decrease in blood cholesterol concentration. This reduction in cholesterol and lipid levels by protein, protein hydrolysates, and peptides can be the result of dietary changes, reduced cholesterol biosynthesis, changes in bile acid synthesis, and reduced absorption of lipid cholesterol and bile acid. Combination drug/diet therapies may reduce the number of drug prescriptions, the progressive rise in “optimal” drug dosage and costs associated with pharmaceutical management of disease. These bioactive vegetable proteins, hydrolysates and peptides may be used in formulation of functional foods, nutraceuticals, and natural drugs because of their health benefit effects suggesting their use as an alternative in treatment of various dyslipidemias, and a potential agent for reducing cardiovascular diseases risk factors.
Palabras Clave: Dyslipemias. Hypiolipidemic effect. Proteins. Peptides.
Nadia Reyna , Rafael Moreno-rojas , Laura Mendoza , Karla Parra , Sergia Linares , Eduardo Reyna , Fernando Cámara-martos
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Ismael San Mauro-martin , Luis Collado-yurrita , Javier Andrés Blumenfeld-olivares , María Ángeles Cuadrado-cenzual , María Elisa Calle-purón , Marta Hernández-cabria , Elena Garicano-vilar , Eva Pérez-arruche , Esperanza Arce-delgado , María José Ciudadcabañas
María Andrea Aimar , Gabriela Pomiglio , Fernando Baccaro , Mario Traverso , Jorge Audisio , Priscila De Feo , Adriana Crivelli , Mariela Flores Lazdin
Ruth Lezama García , Luis Chel Guerrero , Juan José Acevedo-Fernández , David Betancur Ancona
Blanca G. Beltrán Piña , Martha I. González Castro , Francisco Rivas García
Lorea Zubiaga Toro , Jaime Ruiz-Tovar , María J. Castro , Francisco J. Ortiz de Solórzano , Enrique Luque de León , José M. Jiménez , Miguel Á. Carbajo
Victoria Pérez , Gladys Barrera , Sandra Hirsch , Eduardo Lorca , Daniel Carlos Bunout
Claudia C.H. Krüger , Thaise D. Azevedo , Marina Talamini Piltz , Ágatha Transfeld Silva , Lys Mary Bileski Cândido
Carlos Alberto Zúñiga Curz , Claudia C. Calzada Mendoza , Iris Danae Miranda Mondragón , Alfonso Bustamante Bacame , Javier Portilla Robertson , Esther Ocharán Hernández
Bricia López-Plaza , Carmen Gómez Candela , Laura Bermejo López
Ignacio Escribano Ott , Javier Ibáñez Santos
Bruna Morais Faleiros de Paula , Paula Lumy Takeuchi , Helio Vannucchi
Marta Suárez Rodríguez , Violeta Iglesias García , Pilar Ruiz Martínez , Sonia Lareu Vidal , María Caunedo Jiménez , Silvia Martín Ramos , Enrique García López
Rosa M. Ortega , Ana Isabel Jiménez Ortega , Rosa María Martínez García , Esther Cuadrado Soto , Aránzazu Aparicio , Ana M. López-Sobaler
Beatriz Teresita Martín-Márquez , Flavio Sandoval-Garcia , Mónica Vazquez-Del Mercado , Erika-Aurora Martínez-García , Fernanda-Isadora Corona-Meraz , Ana-Lilia Fletes-Rayas , Soraya-Amalí Zavaleta-Muñiz
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Víctor Toro Román , Jesús Siquier Coll , Ignacio Bartolomé Sánchez , María Jesús Figuero Maynar , Marcos Maynar Mariño
Laura Soriano Romaní , Juan Antonio Nieto Fuentes , Lidia Tomás Cobos , Elena Diez Sánchez
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Thais Regina Mezzomo , Marcia Regina Messaggi Gomes Dias , Tatiane Santos , Rosana Marques Pereira
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María Luisa Bordejé
Lliyang Chang , Ronrong Tian , Zili Guo , Luchen He , Yanjuan Li , Yao Xu , Hongmei Zhang
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