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Objective: The aim of this study was to explore the lipid profile in patients with anorexia nervosa (AN), and the changes with refeeding. Methods: The sample comprised 102 AN outpatients (mean age 22.32 ± 3.17). Blood tests, after 12-hour overnight fast, were performed before refeeding (M0) and after weight restoration (M1). Total cholesterol (TC), high-density lipoproteins (HDL), low-density lipoproteins (LDL) and triglycerides (TRG) were determined and the following cardiovascular risk markers were calculated: LDL/HDL and TC/HDL ratios. These cut-off points were considered: TC < 200 mg/dl; HDL > 40 mg/dl; LDL < 100 mg/dl and TRG < 150 mg/dl. Results: The time leading to weight restoration was 8.16 ± 7.35 months. Considering patients with scores higher and lower than the corresponding cut-off points, χ2-test revealed a significant difference (M0-M1) in case of TC (p < 0.05) as well as between LDL/HDL0 and LDL/HDL1 (p < 0.05) and between TC/HDL0 and TC/HDL1 (p < 0.01). Significant differences were found between HDL0 and HDL1 (p < 0.01) and between TRG0 and TRG1 (p < 0.01). Significant and negative associations between BMI0 and TC0 (r = -0.331; p < 0.05) and between TRG0 and HDL0 (r = -0.387; p < 0.05) were found. The association between TRG1 and LDL1 was significant and positive. Discussion: Weight restoration tends to decrease the TC/HDL and LDL/HDL ratios despite a considerable percentage of patients maintain scores on the different variables of the lipid profile usually considered at risk.
Palabras Clave: Anorexia nervosa. Lipid profile. Cardiovascular risk. Refeeding.
Noemí Salvador Soler , Andrés Esteban Roberto Godoy Cumillaf , Jorge Salomón Mella-soto , María Inés Carmona López , Juan José Fernández
Candelaria Martín-González , Ana María Torres-Vega , Emilio González-Reimers , Geraldine Quintero-platt , Camino Fernández-rodríguez , Julio Alvisa-negrín , Adnan Hawari-meilud , Francisco Santolaria-fernández
Javier Darío Pacheco-herrera , Robinson Ramírez-Vélez , Jorge Enrique Correa-bautista
Lorea Zubiaga , Jaime Ruiz-Tovar , Lorena Giner , Juan González , María Del Mar Aguilar , Alejandro García , Rafael Calpena , Manuel Durán
Cristina V Torres Díaz , Gonzalo Martín Peña , Elena Ezquiaga , Marta Navas García , Rafael García De Sola
Carlos Cristi-Montero , Patricio Solís-urra , Fernando Rodríguez-Rodríguez
Raúl Aguilera Eguía
María Teresa Fernández López , Áurea María Gómez Márquez , Laura Casado Vázquez , Susana Alonso Urrutia , María Luisa Bardasco Alonso , María Teresa Rivero Luis , Eva Fernández Pérez , Susana Barreiros Blanco , María Teresa Alves Pérez , José Antonio Mato Mato
Beatriz Voltas-arribas , Ana Artero-Fullana , Juan Carlos Ferrer-garcía , Carlos Sánchez-juan , Cristian Marco-alacid , Pablo Sanz-revert , Lourdes García-blasco
Carmen Gómez Candela , Samara Palma Milla , Alberto Miján-de-la-torre , Pilar Rodríguez Ortega , Viviana Loria Kohen , Rocío Campos Del Portillo , Ángela Martín-Palmero , M.ª Nuria Virgili Casas , Miguel Ángel Martínez Olmos , M.ª Teresa Moríes Álvarez , M.ª José Castro Alija , Ángela Martín-Palmero
Carmen Gómez Candela , Samara Palma Milla , Alberto Miján-de-la-torre , Pilar Rodríguez Ortega , Pilar Matía Martín , Viviana Loria Kohen , Rocío Campos Del Portillo , M.ª Nuria Virgili Casas , Miguel Ángel Martínez Olmos , M.ª Teresa Moríes Álvarez , M.ª José Castro Alija , Ángela Martín-Palmero
Carmen Gómez Candela , Samara Palma Milla , Alberto Miján-de-la-torre , Pilar Rodríguez Ortega , Pilar Matía Martín , Viviana Loria Kohen , Rocío Campos Del Portillo , M.ª Nuria Virgili Casas , Miguel Ángel Martínez Olmos , María Teresa Mories Álvarez , María José Castro Alija , Ángela Martín-Palmero
Pedro Reyes-Castillo , Raquel González-Vázquez , Angélica Gutiérrez-Nava , Felipe Mendoza- Pérez , María del Carmen Navarro González , Alfonso Salgado-Sguayo , Edgard Torres-Maravilla , Lino Mayorga Reyes
Juan Carlos Aristizábal , Alejandro Estrada-Restrepo , Jacqueline Barona
Pedro Delgado-Floody , Felipe Caamaño Navarrete , Constanza Palomino-Devia , Daniel Jerez-Mayorga , Cristian Martínez-Salazar
Mara Segura-Serralta , Conxa Perpiñá , Sonia Císcar , Lorena Blasco , Raul Espert , Cristina Romero-Escobar , José Ramón Domínguez Escribano , Javier Oltra-Cucarella
Norma Serrano , Cristhian Andrés Ojeda , Edna Gamboa Delgado , Claudia Carolina Colmenares Mejia , Doris Cristina Quintero Lesmes
Gonçalo Nunes , Mariana Brito , Marta Patita , Carla Adriana Santos , Jorge Fonseca
Oscar Geovanny Enríquez Martínez , Vivian Cristine Luft , Carolina Perim de Faria , Maria del Carmen Bisi Molina
María del Mar Alañón Pardo , Mónica Ferrit Martín , Miguel Ángel Calleja Hernández , Francisco Morillas Márquez
María Virginia Avena Álvarez , Diego Nicolás Messina , Carla Corte , Jessica Anabella Mussi Stoizik , Aldana Saez , Paola Boarelli , Rafael Pérez Elizalde
Daniel de Luis Román , Olatz Izaola Jáuregui , David Primo Martín , Rocio Aller
Jorge Blanco Anesto , María del Mar Bibiloni , Josep A. Tur
Susana García Calvo , Gonzalo Díaz-Soto , Beatriz Torres Torres , Juan José López Gómez , Aurelia Villar Bonet , Cristina Serrano Valles , Rebeca Jiménez Sahagún , Daniel A. de Luis
Sonia Junquera Bañares , Luis Ramírez Real , Juan Camuñas Segovia , Mercedes Martín García-Almenta , Katiuska Llanos Egüez , José Ignacio Botella Carretero
Salesa Barja , Catalina Le Roy , Cecilia Sepúlveda , Maria Luisa Guzmán , Marithza Olivarez , María José Figueroa
Maria Jesus Lisbona-González , Candela Reyes Botella , Esther Muñoz Soto , Marta Vallecillo-Rivas , Jorge Moreno Fernández , Javier Díaz Castro
Francesco Pazzi , José Carmelo Adsuar , Francisco Javier Domínguez-Muñoz , Miguel Ángel García-Gordillo , Narci Gusi , Daniel Collado-Mateo
Karine Curvello-Silva , Lilian Barbosa Ramos , Claudia Daltro de Sousa , Carla Daltro
Luis A. Moreno-Aznar , María del Carmen Vidal Carou , Ana M. López-Sobaler , Gregorio Varela Moreiras , José Manuel Moreno Villares
Luis Adolfo Santos-Calderón , Juan Manuel Vargas-Morales , Omar Sánchez-Armáss Capello , Margarita Terán-García , Patricia Elizabeth Cossío-Torres , Marisol Vidal Batres , Joan D. Fernandez-Ballart , Celia Aradillas-García
Viviana Loria-Kohen , Rocío Campos del Portillo , Marlhyn Valero Pérez , María Teresa Mories Álvarez , María José Castro Alija , Pilar Matía Martín , Carmen Gómez Candela
Raquel Stocker Pérsico , Oellen Stuani Franzosi
Xochitl Ponce-Martínez , Eloísa Colín-Ramírez , Sonia Rodríguez-Ramírez , Susana Rivera-Mancía , Raúl Cartas-Rosado , Maite Vallejo-Allende
Teodoro Durá-Travé , Fidel Gallinas-Victoriano , María Malumbres Chacón , María Urretavizcaya-Martínez , Paula Moreno González , Lofti Ahmed-Mohamed
María José Lopez Lucas , Salesa Barja , Luis Villarroel del Pino , Pilar Arnaiz , Francisco Mardones
Elena M. Sandoval-Cartagena , Martha Guevara-Cruz , Alfonso Rivera-Duarte , Marcela Hernández-Ortega , Aurora E. Serralde-Zúñiga
Héctor Reynaldo Triana-Reina , Laura Elena Ortiz-Pacheco , Robinson Ramírez-Vélez
Susana del Refugio Ruiz González , Rebeca Monroy Torres , Juan Manuel Malacara , Rodolfo Guardado Mendoza
Carlos Imaz Roncero , Pedro Manuel Ruiz Lázaro , Jesús Pérez Hornero
Nicole Commentz Abarza , Raúl Jara Latorre , Matías Letelier Vuskovic , Lucas Lacalle Quiero , Verónica Irribarra Pastenes , Melina Vogel Martínez , Paola Negrón Granzotto , Daniela Costa Reyes , Camila Contreras Alonso , Gabriela Espinoza Nehgme , Olga Uauy Zirinsky , Maria Fernanda Jara Cordero , Pascuala Urrejola Noguera
Aránzazu López Martínez , Marta Suárez González , Begoña Menéndez Llames , Pilar Palomo Moraleda , Soledad González Muñiz , Juan José Díaz Martín
Edgar Manuel Vásquez-Garibay , Alfredo Larrosa-Haro , Nelly Carolina Muñoz-Esparza , Enrique Romero-Velarde , Elizabeth Guzmán-Mercado , Samuel García-Arellano , Felipe Martínez Limón , José Francisco Muñoz-Valle
Viviana Loria-Kohen , Natalia Montiel Fernández , Bricia López-Plaza , Aránzazu Aparicio
Rocío Campos del Portillo , Samara Palma Milla , Pilar Matía Martín , Viviana Loria-Kohen , Miguel Ángel Martínez Olmos , María Teresa Mories Álvarez , María José Castro Alija , María Ángela Martín Palmero , Elena Carrillo Lozano , Marlhyn Valero-Pérez , Isabel Campos del Portillo , Alejandro Esteban Sirvent Segovia , Pilar Plaza Blázquez , Diana Monserrat de la Cruz López , Francisco Pita Gutiérrez
Angélica María Ballén Torres , María Lola Evia Viscarra , Rodolfo Guardado Mendoza , Daniela Beatriz Muñoz López , Edgar Efrén Lozada Hernández , Luis Fernando Meneses Rojas
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